Figure 1. Cauliflower-like mass at the edge of split-thickness skin graft.

The activity of apical membrane Na channels in the rat cortical collecting tubule was studied during manipulation of the animals' mineralocorticoid status in vivo using a low-Na diet or the diuretic furosemide. Tubules were isolated and split open to expose the luminal membrane surface. Induction of Na channel activity was studied in cell-attached patches of the split tubules. No activity was o...

After surgical excision of hidradenitis suppurativa, reconstruction with a skin graft or a flap is performed when primary closure is not possible. However, the recurrence rate is reportedly high even after wide surgical excision. It is still unclear which reconstruction method provides the lowest recurrence rate. In this report, we present a case of intractable hidradenitis suppurativa in the b...

We developed the novel silk fibroin-based bilayered wound dressing for the treatment of partial thickness wounds. And it showed relevant characteristics and accelerated the healing of full-thickness wounds in a rat model. This study is the clinical evaluation of the bilayered wound dressing to confirm its safety and efficacy for the treatment of split-thickness skin donor sites. The safety test...

BJECTIVES To report our successful experience in managing acquired adult buried penis from nontraumatic origins. We describe a combination of modern techniques involving escutcheonectomy, scrotoplasty, split-thickness skin graft, and fibrin sealant application for genital reconstruction. ETHODS From 2004 through 2007, 5 men with acquired adult buried penis underwent surgical repair at our medic...

Compared with age-matched men, women are resistant to the hypertensive effects of dietary NaCl; however, after menopause, the incidence of salt-sensitive hypertension is similar in women and men. We recently suggested that osmotically inactive Na+ storage contributes to the development of salt-sensitive hypertension. The connective tissues, including those immediately below the skin that may se...

Traditionally, the Na+ cation is thought to be largely restricted to the extracellular compartment, while K+ is stored intracellularly. This balance is maintained by the activity of the Na/K-ATPase sodium pump in the cell membrane. As Na+ and its accompanying anions are the principal extracellular osmoles, extracellular accumulation of Na+ inevitably also leads to fluid retention and expansion ...