نتایج جستجو برای: sarcoma tumors
تعداد نتایج: 244044 فیلتر نتایج به سال:
Most canine tumors of the eyelid are tumors generally encountered in the skin. They are most commonly of epithelial origin and benign. In this report, we describe the cases of two sibling Czech wolfdogs presented, one year apart, with a subcutaneous mass involving the left eyelid. Both lesions were histologically consistent with a diagnosis of subcutaneous fibrosarcoma. Immunohistochemical anal...
PURPOSE Hypoxia is associated with malignant progression and poor outcome in several human tumors, including soft tissue sarcoma. Recent studies have suggested that carbonic anhydrase (CA) IX is an intrinsic marker of hypoxia, and that CA IX correlates with poor prognosis in several types of carcinoma. The aim of this study was to quantify the extent of CA IX expression and to investigate wheth...
Modern multimodal treatment has significantly increased survival for patients affected by hematologic malignancies, especially in childhood. Following remission, however, the risk of developing a further malignancy is an important issue. The long-term estimated risk of developing a sarcoma as a secondary malignancy is increased severalfold in comparison to the general population. Ewing's sarcom...
UNLABELLED Pediatric Ewing sarcoma is characterized by the expression of chimeric fusions of EWS and ETS family transcription factors, representing a paradigm for studying cancers driven by transcription factor rearrangements. In this study, we describe the somatic landscape of pediatric Ewing sarcoma. These tumors are among the most genetically normal cancers characterized to date, with only E...
X-irradiated (400 R) CBF (BALB/c 9 X C57BL/6 o") FI mice inoculated with BALB/c Moloney sarcoma cells developed more tumors and exhibited fewer tumor regressions than normal CBF controls. Most of the latter and only one of the former produced detectable fluorescent antibody as tested against BALB/c Moloney lymphoma cells. BALB/c Moloney sarcoma cells incubated with spleen cells from C57BL/6 mic...
UNLABELLED Ewing sarcoma is a primary bone tumor initiated by EWSR1-ETS gene fusions. To identify secondary genetic lesions that contribute to tumor progression, we performed whole-genome sequencing of 112 Ewing sarcoma samples and matched germline DNA. Overall, Ewing sarcoma tumors had relatively few single-nucleotide variants, indels, structural variants, and copy-number alterations. Apart fr...
Primitive myxoid mesenchymal tumor of infancy (PMMTI) is an aggressive with a high rate local recurrence, rare metastasis and poor response to chemotherapy.PMMTI soft-tissue sarcoma that preferentially affects infants. It isolated from the group infantile fibrosarcomas or myofibroblastic tumors. PMMTI differs other tumors in clinical course, morphological features primarily molecular genetic ch...
Among the group of small round cell tumors of kidney Ewing's sarcoma/PNET is a very rare entity which has aggressive clinical course. We report a case of renal mass in 24 years old male which was histologically diagnosed as small round cell tumor of kidney. Arrangement of the malignant cell along with vascular network in a filigree pattern was suspicious for a diagnosis of Ewing's sarcoma/PNET ...
Primary cardiac sarcoma is a rare malignant myocardial neoplasm that does not exhibit gender predominance or age predilection. The classification of these tumors includes several subtypes, of which synovial sarcoma is a rare manifestation. When present, these tumors portend a poor prognosis with high morbidity and mortality that is attributable to their inherent infiltrative capacity, especiall...
Nuclear Medicine examinations are integral in the management of children with cancer. Imaging with conventional gamma camera systems, hybrid gamma camera systems and radiopharmaceuticals; and with positron emission tomography (PET) and PET/ CT systems and positron emitters can be used for staging, metastatic work-up, surveillance follow-up, therapeutic response assessment and treatment. Tumors ...
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