High treatment failure rates and the need for prolonged antimicrobial therapy for osteomyelitis and implant-associated infections suggest that antimicrobial bone penetration may be incomplete. Assessment of the bone pharmacokinetics of antimicrobials is challenged by a lack of validated methods. In this study, 1000 mg of vancomycin was administered as a single dose over 100 min to eight female ...

Texas horned lizards (Phrynosoma cornutum; hereafter THL) were once abundant throughout Texas; however, their distribution and abundance have decreased, currently they are listed as a threatened species in the state. Detection of THL can be difficult because cryptic nature sporadic distribution. Using indirect signs such fecal pellets (i.e., scat) to determine occupancy is widely practiced surv...

in order to study the role of the kidney in fish osmoregulation, freshwater acclimatized juvenile spottedscat (scatophagus argus l.) were subjected to four different salinities and observed for histomorphometricchanges of the kidney at 1, 2, 10 and 15 days post transfer time points. the overall morphological changesdisplayed by fish kidney included significant decrease in the density of collect...

Objectives Rugby Union has adapted the Sports Concussion Assessment Tool (SCAT) into an abridged off-field concussion screen and complete SCAT is used during diagnostic screens performed after head impact events. No firm guidelines exist as to what should be considered “abnormal” warrant further evaluation. This study evaluates performances in 13,479 baseline assessments, proposes clear referen...

Aim . To compare the expression of enzymes ceramide de novo synthesis pathway in cardiac adipose tissue (AT) and blood vessels patients with coronary artery disease (CAD) acquired heart defects. Material methods The study included 20 CAD 18 aortic stenosis/regurgitation. Biopsies subcutaneous, epicardial, perivascular AT (SCAT, EAT, PVAT, respectively) were obtained during surgery. Quantitative...

A new autosomal recessive mouse mutation, scat (severe combined anemia and thrombocytopenia), causes intermittent episodes of severe bleeding in the homozygote. At birth, affected mice are pale with intradermal petechiae and bruises on exposed surfaces. Central nervous system (CNS) bleeding occurs in 22% of the mice. Gastrointestinal (GI) hemorrhaging and splenomegaly are noted in moribund mice...

Recently, detection dogs have been utilized to collect fecal samples from cryptic and rare mammals. Despite the great promise of this technique for conservation biology, its broader application has been limited by the high cost (tens to hundreds of thousands of dollars) and logistical challenges of employing a scat-detection dog team while conducting international, collaborative research. Throu...

Large cats feeding habits have been studied through two main methods: scat analysis and the carcasses of prey killed by monitored animals. From November 2001 to April 2004, we studied jaguar predation patterns using GPS telemetry location clusters on a cattle ranch in southern Pantanal. During this period, we recorded 431 carcasses of animals preyed upon by monitored jaguars. Concurrently, we c...

The 1970 SS Arrow incident in Chedabucto Bay, Nova Scotia (NS) was a milestone event Canada's oil spill response history and has been used by Environment Climate Change Canada (ECCC) for ongoing research almost 50 years. In August of 2015, the remaining sunken section ARROW released Bunker C from its tanks some sections shorelines impacted were affected once again. Canadian Coast Guard led 2015...