FORD J. W. and BLANKESPOOR H. D. 1979. Scanning electron microscopy of the eggs of three human schistosomes. Znternational Journalfor Parasitology 9: 141-145. The surface of the eggs of Schistosoma haematobium, S. japonicum and S. mansoni, examined by scanning electron microscopy, are covered with microspines. The spines of S. mansoni and S. haematobium are essentially similar; however, in S. j...

BACKGROUND Schistosome infections are often clinically silent, but some individuals develop severe pathological reactions. In several disease processes, T-helper 17 (Th17) cells have been linked to tissue injuries, while regulatory T cells (Tregs) are thought to downmodulate inflammatory reactions. We assessed whether bladder pathology in human Schistosoma haematobium infection is related to th...

BACKGROUND Over 650 million people globally are at risk of schistosomiasis infection, while more than 200 million people are infected of which the higher disease rates occur in children. Eighty three students between 6-20 years (mean 12.45 ± 3.2) from Quran School for boys in Radwan village, Gezira state were recruited to investigate for the relationship between the genetic diversity of Schisto...

Hybridization is a fascinating evolutionary phenomenon that raises the question of how species maintain their integrity. Inter-species hybridization occurs between certain Schistosoma can cause important public health and veterinary issues. In particular hybrids haematobium S . bovis associated with humans animals respectively are frequently identified in Africa. Recent genomic evidence indicat...

An intervention study was conducted in Khamir, north of Sana'a, for control of urinary schistosomiasis using chemotherapy and health education. The validity and cost-effectiveness of reagent strips as a rapid diagnostic tool to screen for Schistosoma haematobium infection was also assessed along with visible haematuria. Prevalence of S. haematobium infection 14 months post-intervention fell fro...

BACKGROUND Urogenital schistosomiasis is a major public health problem in sub-Saharan Africa, and routine programs for screening and treatment of pregnant women are not established. Mefloquine-currently evaluated as a potential alternative to sulfadoxine-pyrimethamine as intermittent preventive treatment against malaria in pregnancy (IPTp)-is known to exhibit activity against Schistosoma haemat...

Artesunate is a highly effective antimalarial and there is some evidence that it is also active against schistosome infections. We therefore investigated whether treatment with artesunate of acute malaria in Senegalese children had an impact on their level of infection with Schistosoma haematobium. Twenty-seven children who were entered into a clinical trial of antimalaria treatment were excret...

(McCully et al. 1976 loc. cit.). In Egypt there are distinct areas where either S. mansoni or S. haematobium is predominant (HF el Sayed et al. 1995 Am J Trop Med Hyg 52: 194-198). In Angola, in the northern part of the country where the patient comes from, S. haematobium predominates. In Brazil, schistosomiasis is due to S. mansoni with no autoctones cases of S. haematobium described. The inte...

BACKGROUND Microscopy remains the gold standard in the diagnosis of neglected tropical diseases. As resource limited, rural areas often lack laboratory equipment and trained personnel, new diagnostic techniques are needed. Low-cost, point-of-care imaging devices show potential in the diagnosis of these diseases. Novel, digital image analysis algorithms can be utilized to automate sample analysi...

BACKGROUND Schistosoma infection is thought to lead to down-regulation of the host's immune response. This has been shown for adaptive immune responses, but the effect on innate immunity, that initiates and shapes the adaptive response, has not been extensively studied. In a first study to characterize these responses, we investigated the effect of Schistosoma haematobium infection on cytokine ...