Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics. These venoms are associated with high morbility and mortality, especially among children. Victims of envenoming by a scorpion suffer a variety of pathologies, involving mainly b...

Introduction Scorpion sting is an important public health problem in some countries, including Iran. This study aimed to describe the demographics of a large number of these victims in some endemic areas of Iran. Methods This cross-sectional study evaluated baseline characteristics, clinical findings, management, and disposition of scorpion stung cases in 26 cities of 4 provinces in the south...

backgrounds and aims : in the tropical regions of iran, scorpion stings are one of the most important medical and health problems. knowing about their epidemiologic aspects might lead to the employment of appropriate preventive methods. therefore, these studies were done in qom province for this purpose. materials and methods : this research is a descriptive cross-sectional study which has been...

Abstract Scorpionic accidents are a major public health problem due to the high occurrence with potential seriousness. In this manner, research aimed analyze of scorpionic in municipality northeastern Brazil. An exploratory, descriptive study was made, quantitative approach, using secondary data which gotten from Notifiable Diseases Information System (SINAN), 2008 2018. Data such as neighborho...

Painful venoms are used to deter predators. Pain itself, however, can signal damage and thus serves an important adaptive function. Evolution to reduce general pain responses, although valuable for preying on venomous species, is rare, likely because it comes with the risk of reduced response to tissue damage. Bark scorpions capitalize on the protective pain pathway of predators by inflicting i...

Accidents caused by scorpion stings, mainly affecting children, are considered an important cause of morbidity and mortality in tropical countries. Clinical studies demonstrate the relevant role of systemic inflammatory events in scorpion envenoming. However, remains poorly understood whether the major lethal component in Tityus serrulatus venom, tityustoxin (TsTX), is able to induce inflammato...

Scorpion stings are a common occurrence in Saudi Arabia. The majority of cases present with local pain at the site of envenomation, and follow a benign clinical course. Severe systemic toxicity and mortality are uncommon. Reported deaths have been attributed to a primary effect of the venom on the cardiovascular system. Toxicity of envenomation varies between species and within the same species...

Scorpion sting-induced human envenomation provokes an intense inflammatory reaction. However, the mechanisms behind the recognition of scorpion venom and the induction of mediator release in mammalian cells are unknown. We demonstrated that TLR2, TLR4 and CD14 receptors sense Tityus serrulatus venom (TsV) and its major component, toxin 1 (Ts1), to mediate cytokine and lipid mediator production....

This epidemiological review was carried out to display the magnitude and the geographic distribution of scorpion envenomation in Iran with focus on the southwestern region of Iran, particularly. The Iranian recognized scorpions belonging to two families, including Buthidae and Scorpionidae. Buthidae family consists of 14 genuses, 26 species, and 18 sub-species, while Scorpionidae family has thr...