The toxicity of endodontic materials is reviewed. The patient may be exposed by constituents leaching from the unset and set sealer and by accidental overfilling of the root canal. For most patients the exposure is believed to be below the threshold for a toxic effect. Most sealers exhibited a cytotoxic response, especially unset and the responses diminished with time after setting. Unset and n...

Introduction: Optimal radiopacity is one of the properties required for a root canal sealer that helps the distinction between the sealer and surrounding anatomic structures and evaluation of the quality of root filling. So, the purpose of this study was to evaluate the radiopacity of six root canal sealers at different focal distances. Materials and Methods: In this in vitro study, six endodo...

the aim of this study was to evaluate and compare the cytotoxicity induced by two resin-based sealers, 2seal and ah plus, in two osteoblast-like cell lines, mg-63 and saos-2. using sterile discs of both sealers in complete media, 24- and 72-h extracts were prepared. the extracts were exchanged with saos-2 or mg-63 cell culture media at 75% confluence, and after 24 h incubation, cell viability t...

introduction: endodontic sealers are in direct contact with periradicular tissues and play a critical role in regeneration and pathogenesis of periradicular diseases. the aim of this study was to compare cytotoxicity of four different types of sealers including ah plus, sankin, tubliseal ewt and apexit as well as their effect on cytokine release of l929 fibroblasts. materials and methods: in th...

BACKGROUND The aim of the present study is to evaluate and compare the cytotoxic effects of eight root canal sealers (BioRoot RCS, TotalFill BC Sealer, MTA Fillapex, Sealapex, AH Plus, EasySeal, Pulp Canal Sealer, N2) on immortalized human gingival fibroblasts over a period of 24, 48 and 72 hours. MATERIAL AND METHODS Immortalized human gingival fibroblast-1 HGF-1 (ATCC CRL-2014) were incubat...

OBJECTIVE The aim of this in vitro study was to evaluate the bond strength of different root canal sealers to dentin. MATERIAL AND METHODS Forty extracted single-rooted human teeth were examined and the coronal and middle thirds of the canals were prepared with a 1.50 mm post drill (FibreKor Post System, Pentron). The teeth were allocated in two experimental groups, irrigated with 2.5% NaOCl+...

Background and Aim: Tubular penetration of root canal sealers prevents filling material displacement and overgrowth of microorganisms in dentinal tubules. The aim of this study was to compare the tubular penetration of AH26, EasySeal, and SureSeal sealers in single-rooted teeth using scanning electron microscopy (SEM). Materials and Methods: Fifty human single-rooted teeth were included in thi...

INTRODUCTION The aim of the present experimental study was to evaluate the push-out bond strength of Dorifill, Epiphany and MTA-Fillapex sealers to root canal dentin in presence and absence of smear layer (SL). METHODS AND MATERIALS Sixty human single-rooted teeth were selected and divided into six groups (n=10). The canal irrigation protocol in groups 1, 3 and 5 consisted of 2.5% NaOCl durin...

BACKGROUND The strong link between sealer solubility and periapical reinfection indicates that water solubility of new sealers should be studied. This study aimed to assess the water solubility of five root canal sealers (AH-26, Topseal, 2-Seal, Acroseal, and Roeko Seal Automix [RSA]). MATERIALS AND METHODS In this in vitro experimental study, 30 specimens were fabricated from each of the abo...