نتایج جستجو برای: selective estrogen receptor modulators

تعداد نتایج: 788619  

Journal: :Folia histochemica et cytobiologica 2011
Monika Zbucka-Kretowska Naama Marcus-Braun Cyril Eboue Geneviève Abeguile Slawomir Wolczynski Marie Laure Kottler Peter Von Theobald

The precise role of estrogen in the pathogenesis of pelvic organ prolapse (POP) is still unclear, while the results concerning the effect of selective estrogen receptor modulators on pelvic organ prolapse are contradictory. Our aim was to test whether alteration in the expression of estrogen receptors in the pelvic floor of pre- and post-menopausal women is related to genital prolapse status. T...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2006
Chiara Bolego Elisabetta Vegeto Christian Pinna Adriana Maggi Andrea Cignarella

The cloning of estrogen receptors (ERs) and generation of ER-deficient mice have increased our understanding of the molecular mechanisms underlying the cardiovascular effects of estrogen. It is conceivable that clinical trials of estrogens so far failed to improve cardiovascular health because of the poor ER isoform selectivity and tissue specificity of endogenous hormones as well as incorrect ...

Journal: :Therapeutic Advances in Musculoskeletal Disease 2012

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