Background: Gel-cream formulations used as cosmetics can present various textures. They may be fluid or semisolid, being highly influenced by their composition. These presentations require a complete study to obtain information about the physical stability and consistency of product possible interaction between its compounds. In this context, aimed develop cosmetic using carrageenan argan oil a...

Objective: This study aimed to develop a topical nanoemulsion using clove oil and ethanol extract of catharanthus roseus (L.) G. for antioxidant antibacterial dosage form. Methods: The was produced spontaneous emulsification method. formulation carried out tween 80 pluronic 127 as surfactants with different concentrations (0.5–2%). characterizations the formula included organoleptic test, homog...

A semisolid dosage form of clonazepam (CZP), administered to the oral cavity between the lower gum and bottom lip with small volume of saline, was developed to obtain the stable dosage which can replace the injection dosage form. Semisolid dosage forms were prepared using a mixture of CZP/(polyethylene glycol 1500 (PEG))/(oleic acid (OA)) at the ratios of 1/39/0, 1/37/2 and 2/36/2 (w/w), named ...

In the present work, stress was given for improvised local action of the drug with the addition of mucoadhesive polymer in the formulation. Oral mucoadhesive semi solid gel was prepared for the treatment of oral sub mucous fibrosis, which provides effect for extended periods of time. Curcumin was taken as a model drug as it exhibits profound antitumeric & antimutogenic activity. The semisolid p...

We have established cell lines from six human squamous cell carcinomas (SCC) of the epidermis and tongue, using culture methods previously developed for clonal growth and serial cultivation of normal keratinocytes. The SCC lines all form rapidly growing, well-differentiated SCC's or progressively growing squamous cysts in nude mice. In contrast to normal keratinocytes, SCC cells form unstratifi...

Production of cold active lipase by semisolid state fermentation involves the use of agroindustrial residues. In the present study, semisolid state fermentation was carried out for the production of cold active lipase using Micrococcus roseus, isolated from soil samples of Gangotri glaciers, Western Himalayas. Among various substrate tested, groundnut oil cake (GOC) favored maximal yield of lip...

The aim of the study was to select the optimal composition of semisolid using natural materials, and to evaluate the quality of such preparation. Investigation of rheological properties, evaluation of sensory characteristics, detection and identification of phenolic acids using high-performance liquid chromatography (HPLC) were performed. The results of the rheological investigations and the st...

background: every year many organizations formulate a code of ethics (coe) but when it comes to implementing, it does not achieve the desired purposes. ineffectiveness of coes can stem from different factors and surely, one of them is bad formulation. this research was conducted to identify the barriers to effective formulation of coes in one of the main state universities of medical sciences i...

The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper describes the in vitro assessment of acyclovir (ACV) into porcine skin from commercial formulations with etermination of drug concentration in different layers of cutaneous tissue to correlate with effective antiviral concentration in or...

The interconversion of atmospheric organic particles among solid, semisolid, and liquid phases is of keen current scientific interest, especially for particles of secondary organic material (SOM). Herein, the influence of phase on ammonia uptake and subsequent particle-phase reactions was investigated for aerosol particles of adipic acid and α-pinene ozonolysis SOM. The nitrogen content of the ...