Objective. Visfatin is a member of the adipocytokines with pro-fibrotic, pro-inflammatory and immunomodulating properties potentially implicated in the pathogenesis of certain fibrotic and inflammatory autoimmune diseases. In this study, we investigated the clinical significance of serum visfatin levels and its contribution to the developmental process in SSc. Methods. Serum visfatin levels wer...

A prospective study was performed to evaluate the diagnostic accuracy of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) levels, measured simultaneously in serum and pleural fluid, in identifying pleural effusions due to heart failure. Pleural fluid and serum samples from all patients presenting for thoracentesis between April 2004 and May 2005 were simultaneously collected. The discrimin...

aviecennia marina (avicenniaceae) is an endemic plant that widely distributed in the southern parts of iran. this plant has been used as treatment of rheumatism arthritis among the inhabitants of southern parts of iran. the avicennia marina hydroalcoholic extract was prepared and its protective efficacy was investigated using measurement of ankle diameter, total wbc and rbc count, esr, and pro-...

BACKGROUND Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were useful to reclassify strokes of undetermined etiology. METHODS We included 262 ...

S100A12 is elevated in the circulation in patients with chronic inflammatory diseases and recent studies indicate pleiotropic functions. Serum amyloid A induces monocyte cytokines and tissue factor. S100A12 did not stimulate IL-6, IL-8, IL-1β or TNF-α production by human peripheral blood mononuclear cells but low amounts consistently reduced cytokine mRNA and protein levels induced by serum amy...

Aviecennia marina (Avicenniaceae) is an endemic plant that widely distributed in the Southern parts of Iran. This plant has been used as treatment of rheumatism arthritis among the inhabitants of Southern parts of Iran. The Avicennia marina hydroalcoholic extract was prepared and its protective efficacy was investigated using measurement of ankle diameter, total WBC and RBC count, ESR, and Pro-...

Aviecennia marina (Avicenniaceae) is an endemic plant that widely distributed in the Southern parts of Iran. This plant has been used as treatment of rheumatism arthritis among the inhabitants of Southern parts of Iran. The Avicennia marina hydroalcoholic extract was prepared and its protective efficacy was investigated using measurement of ankle diameter, total WBC and RBC count, ESR, and Pro-...

Objective. To study the concentration of pro-inflammatory cytokine interleukin-17 in blood serum patients with multiple sclerosis.
 Materials and methods. 68 sclerosis were examined. The severity neurological deficit was assessed by EDSS MSFC. determined method enzyme-linked immunosorbent assay.
 Results. It found that sclerosis, serum, normal group as a whole, induced effect immunomo...

Objective: In the present study, we aimed to examine the effect of troxerutin treatment on levels of brain-derived neurotrophic factor (BDNF), and tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), as pro-inflammatory cytokines, in the blood and hippocampus of high-fat diet (HFD) fed dams and their male offspring. <span ...

The aim of our study is to elucidate changes in the content pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) anti-inflammatory cytokines interleukin-10 (IL-10) blood serum guinea pigs dynamics experimental periodontitis immobilization stress.The combined pathology (experimental stress) accompanied by a pronounced progression proinflammatory group - TNF-α IL-6 against ba...