While the cornerstone of monitoring following severe pediatric traumatic brain injury is serial neurologic examinations, vital signs, and intracranial pressure monitoring, additional techniques may provide useful insight into early detection of evolving brain injury. This paper provides an overview of recent advances in neuromonitoring, neuroimaging, and biomarker analysis of pediatric patients...

OBJECTIVE To assess health-related quality of life in individuals with severe traumatic brain injury at 12 months post-injury, applying the Quality of Life after Brain Injury (QOLIBRI) instrument, and to study the relationship between injury-related factors, post-injury functioning and health-related quality of life. DESIGN/SUBJECTS The study is part of a prospective, Norwegian multicentre st...

chiari malformation type i (cm-i) is a congenital disorder, which is basically a tonsillar herniation (≥ 5 mm) below the foramen magnum with or without syringomyelia. the real cause behind this malformation is still unknown. patients may remain asymptomatic until they engender a deteriorating situation, such as cervical trauma. the objective of this case report is to give a broad perspective on...

PRIMARY OBJECTIVE The consequences of pre-morbid factors in adults with severe traumatic brain injury have not been widely addressed. This study aimed to determine whether being unemployed or on sick leave before injury influences long-term health-related quality-of-life (HRQoL) and functioning in patients with severe traumatic brain injury. SUBJECTS Fifty-one consecutive patients were studie...

A basic description of severity and frequency is needed for planning healthcare delivery for any disease process. In the case of traumatic brain injury, severity is typically categorized into mild, moderate, and severe with information from a combination of clinical observation and self-report methodologies. Recent US civilian epidemiological findings measuring the frequency of mortality and mo...

Transplantation of umbilical cord-derived mesenchymal stem cells (UC-MSCs) for repair of traumatic brain injury has been used in the clinic. Hyperbaric oxygen (HBO) treatment has long been widely used as an adjunctive therapy for treating traumatic brain injury. UC-MSC transplantation combined with HBO treatment is expected to yield better therapeutic effects on traumatic brain injury. In this ...

INTRODUCTION Traumatic brain Injuries represents a significant cause of morbidity and mortality worldwide and road traffic crashes accounts for a significant proportion of these injuries. However, access to neurosurgical care is poor in low income countries like Tanzania. The aim of this study was to assess the management and outcome of Traumatic brain injury patients at a tertiary level health...

OBJECTIVE To evaluate the course and identify determinants of community integration for up to 3 years following moderate to severe traumatic brain injury. DESIGN Prospective cohort study. PATIENTS A total of 119 moderate to severe traumatic brain injury patients aged 16-67 years. METHODS The Community Integration Questionnaire was completed at 3, 6, 12, 18, 24 and 36 months post-injury. R...

OBJECTIVE To investigate the occurrence and severity of traumatic brain injury in patients with traumatic spinal cord injury. DESIGN Cross-sectional study with prospective neurological, neuropsychological and neuroradiological examinations and retrospective medical record review. PATIENTS Thirty-one consecutive, traumatic spinal cord injury patients on their first post-acute rehabilitation ...