OBJECTIVES To investigate the progression of joint damage in early rheumatoid arthritis (RA) using magnetic resonance imaging (MRI) of the wrist and determine whether this technique can be used to predict prognosis. METHODS An inception cohort of 42 early patients has been followed up prospectively for one year. Gadolinium enhanced MRI scans of the dominant wrist were obtained at baseline and...

background: radiographic examination of tmj is indicated when there are clinical signs of pathological conditions, mainly bone changes that may influence the diagnosis and treatment planning. the purpose of this study was to evaluate and to compare the validity and diagnostic accuracy of uncorrected and corrected sagittal tomographic images in the detection of simulated mandibular condyle erosi...

The role of glucocorticoids released in response to stress in the pathogenesis of stress-induced gastric erosions has been reevaluated. Gastric erosions elicited in male rats by 3-h cold-restraint or water-restraint stresses were studied after acute reduction of corticosterone release or occupation of glucocorticoid receptors by the antagonist RU-38486 during stress. Stress-induced corticostero...

We read with interest the pictorial essay on ultrasonography of bone erosions by Grassi and colleagues. The presented site-specific comparison of radiographic and sonographic imaging of metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joint sites in rheumatoid subjects suggests strongly a homology of the erosive lesions, as visualised by these diVerent imaging modalities. A recently publ...

introduction: cholesteatoma is traditionally diagnosed by otoscopic examination and treated by surgery. the necessity for imaging in an uncomplicated case is controversial. this study was planned to investigate the usefulness of a preoperative high-resolution computed tomography (hrct) scan in depicting the status of middle ear structures in the presence of cholesteatoma and also to compare the...

A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells for histological diagnosis. Subsequent biopsy specimens from the peripheral mucosa containing the...