نتایج جستجو برای: shotgun cellular systems
تعداد نتایج: 1586228 فیلتر نتایج به سال:
The genome sequence of the soil bacterium Sphingobacterium sp. strain HMA12, the culture supernatant of which exhibited endo-β-N-acetylglucosaminidase (ENGase) activity, was examined for ENGase-encoding genes. Here, we report the characterization of new genes of ENGases, obtained by whole-genome shotgun sequencing, that are capable of specifically hydrolyzing fucose-containing oligosaccharides.
Since the end of 2001, we have conducted a project to isolate and determine entire sequences of mouse cDNA clones which encode the polypeptides corresponding to human KIAA proteins. Towards the ultimate goal of this project to clarify the biological functions of KIAA genes, we have set production of antibodies against mouse KIAA gene products based on their sequence information as the next impo...
Plastic is exceedingly abundant in soils, but little known about its ecological consequences for soil microbiome functioning. Here we report the impacts of polyethylene and biodegradable Ecovio BI-OPL plastic films buried alpine soils 5 months on genetic potential using shotgun metagenomics. The was more affected by than polyethylene. Fungi, ?- ?-Proteobacteria dominated films. showed signs deg...
We have developed an integrated suite of algorithms, statistical methods, and computer applications to support large-scale LC-MS-based gel-free shotgun profiling of complex protein mixtures using basic experimental procedures. The programs automatically detect and quantify large numbers of peptide peaks in feature-rich ion mass chromatograms, compensate for spurious fluctuations in peptide sign...
Protein turnover is a well-controlled process in which polypeptides are constantly being degraded and subsequently replaced with newly synthesized copies. Extraction of composite spectral envelopes from complex LC/MS shotgun proteomics data can be a challenging task, due to the inherent complexity of biological samples. With partial metabolic labeling experiments this complexity increases as a ...
Many protein-protein docking protocols are based on a shotgun approach, in which thousands of independent random-start trajectories minimize the rigid-body degrees of freedom. Another strategy is enumerative sampling as used in ZDOCK. Here, we introduce an alternative strategy, ReplicaDock, using a small number of long trajectories of temperature replica exchange. We compare replica exchange sa...
چکیده در این پایاننامه ابتدا فضاهای متریک فازی را به صورت مشاهدهگرایانه بررسی میکنیم. فضاهای متریک فازی و توپولوژی تولید شده توسط این متریک معرفی شدهاند. سپس بر اساس فضاهایی که در فصل اول معرفی شدهاند آشوب توپولوژیکی، مینیمالیتی و مجموعههای متقاطع در شیوههای مختلف بررسی شده- اند. در فصل سوم مفهوم مجموعههای جاذب فازی به عنوان یک مفهوم پایهای در سیستمهای نیم-دینامیکی نسبی، تعریف شده است. ...
The candidate division Korarchaeota comprises a group of uncultivated microorganisms that, by their small subunit rRNA phylogeny, may have diverged early from the major archaeal phyla Crenarchaeota and Euryarchaeota. Here, we report the initial characterization of a member of the Korarchaeota with the proposed name, "Candidatus Korarchaeum cryptofilum," which exhibits an ultrathin filamentous m...
This paper develops an integer mathematical programming model to design the cellular manufacturing systems under data envelopment analysis. Since workers have an important role in doing jobs on machines, assignment of workers to cells becomes a crucial factor for fully utilization of cellular manufacturing systems (CMS). The aim of the proposed is to minimize backorder costs and intercellul...
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