Markov fluid models with fluid level dependent behaviour are considered in this paper. One of the main difficulties of the analysis of these models is to handle the case when in a given state the fluid rate changes sign from positive to negative at a given fluid level. We refer to this case as zero transition. The case when this sign change is due to a discontinuity of the fluid rate function r...

Dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) is a DC-specific C-type lectin that plays an important role in recognizing and capturing pathogens, DC migration and initiation of T cell responses. Here, we show that anti-P-selectin lectin-EGF domain monoclonal antibody (PsL-EGFmAb), originally prepared for blockade of the adhesive molecule P-selecti...

The concept of semicopula plays a fundamental role in the definition of a universal integral. We present an extension of semicopula to the case of symmetric interval [−1,1]. We call this extension bipolar semicopula. The last definition can be used to obtain a simplified definition of the bipolar universal integral. Moreover bipolar semicopulas allow for extension of theory of copulas to the in...

This paper presents solne inrprovements to the matrix-sigll-fllnction algorithn~ for the alge\,raic Riccati equation. A simple reorganization changes nonsynnnetric watrix inversion5 into syinmetric niatrix inversions. Scaling accelerates convergence of the basic iteration ant1 yields a new qnadratic formula for certain 2-by-2 algebraic Riccati eqnation5. Numerical experience suggests the algori...

The Liouville function λ(n) is the completely multiplicative function whose value is −1 at each prime. We develop some algorithms for computing the sum T (n) = ∑n k=1 λ(k)/k, and use these methods to determine the smallest positive integer n where T (n) < 0. This answers a question originating in some work of Turán, who linked the behavior of T (n) to questions about the Riemann zeta function. ...

In this paper we present modiied algorithms for computing deeating subspaces of matrix pencils by means of the matrix sign function. Speciically, our new algorithms reduce the number of iterations to half, cut the cost of each Newton iteration by more than 50%, and improve the accuracy of the computed deeating subspaces. The matrix sign function is thus revealed as an eeective technique for app...

Natural selection is an important factor influencing variation in the human genome, but most genetic studies of natural selection have focused on variants with unknown phenotypic associations. This trend is changing. New studies are rapidly revealing the effects of natural selection on genetic variants of known or likely functional importance.

In 1895 Trendelenburg described his sign to determine the integrity of hip function. We found the sign to be positive in a patient whose hip was clinically and radiologically normal, and therefore investigated this in other patients. We confirmed that a medial shift of the mechanical axis of the leg below the hip may cause a positive Trendelenburg sign. This has not been previously described.