We report SInC (SNV, Indel and CNV) simulator and read generator, an open-source tool capable of simulating biological variants taking into account a platform-specific error model. SInC is capable of simulating and generating singleand paired-end reads with user-defined insert size with high efficiency compared to the other existing tools. SInC, due to its multi-threaded capability during read ...

in this paper, a numerical solution for a system of linear fredholm integro-differential equations by means of the sinc method is considered. this approximation reduces the system of integro-differential equations to an explicit system of algebraic equations. the exponential convergence rate $o(e^{-k sqrt{n}})$ of the method is proved. the analytical results are illustrated with numerical examp...

This talk consists of a proof of part of Stenger’s SINC-PACK computer package (an approx. 400-page tutorial + about 250 Matlab programs) that one can always achieve separation of variables when solving linear elliptic, parabolic, and hyperbolic PDE (partial differential equations) via use of Sinc methods. Some examples illustrating computer solutions via SINC-PACK will nevertheless be given in ...

This paper gives a brief review of Sinc methods, with emphasis on the matrices of Sinc methods. A novel procedure is presented, based on Sinc convolution, for solving a Poisson problem over a rectangular region. Although some of the work of Gragg and Reichel may already be applied to the solution of Sinc{matrix problems, this paper also points to new directions of matrix research.

This paper introduces a formalism named SINC aimed at the design and verication of synchronous concurrent systems. The components of this formalism are a transition system and a rst-order linear-time temporal logic. The SINC transition system adopts a synchronous computation model, includes a method to solve write-con icts, and represents transitions as possibly non-terminating imperative comma...

This paper introduces a formalism named SINC aimed at the design and verification of synchronous concurrent systems. The components of this formalism are a transition system and a first-order linear-time temporal logic. The SINC transition system adopts a synchronous computation model, includes a method to solve write-conflicts, and represents transitions as possibly non-terminating imperative ...

SINC, a new type III secreted protein of the avian and human pathogen Chlamydia psittaci, uniquely targets the nuclear envelope of C. psittaci-infected cells and uninfected neighboring cells. Digitonin-permeabilization studies of SINC-GFP-transfected HeLa cells indicate that SINC targets the inner nuclear membrane. SINC localization at the nuclear envelope was blocked by importazole, confirming...

Multifunctional theranostic platforms capable of concurrent near-infrared (NIR) fluorescence imaging and phototherapies are strongly desired for cancer diagnosis and treatment. However, the integration of separate imaging and therapeutic components into nanocarriers results in complex theranostic systems with limited translational potential. A single agent-based theranostic nanoplatform, theref...

We consider a class of interpolation algorithms, including the least-squares optimal Yen interpolator, and we derive a closed-form expression for the interpolation error for interpolators of this type. The error depends on the eigenvalue distribution of a matrix that is specified for each set of sampling points. The error expression can be used to prove that the Yen interpolator is optimal. The...