dried oleander leaves at single lethal dose of 110 mg/kg body weight were administered orally to fivenative female goats. clinical signs of toxicosis in goats began to appear about 1 hr after receiving theoleander and included abdominal pain, ruminal atony and tympany, frequent urination, bradycardia,tachycardia, tachyarrhythmia, depression, weakness and convulsive movement and death at the end...

OBJECTIVES The purpose of this study was to determine the patterns of autonomic nerve activity in congestive heart failure (CHF). BACKGROUND The relationship between autonomic nerve activity and cardiac arrhythmias in CHF is unclear. METHODS We implanted radiotransmitters in 6 dogs for continuous (24/7) simultaneous monitoring of left stellate ganglion nerve activity (SGNA), vagal nerve act...

Introduction Inappropriate sinus tachycardia (IST) is a rare disorder defined as a nonparoxysmal rhythm originating from the sinus node associated with palpitations with a resting heart rate 4100 beats/min and a 24-hour mean heart rate 490 beats/min, with all other potential causes of sinus tachycardia excluded. Patients with IST may experience debilitating palpitations, lightheadedness, chest ...

BACKGROUND Prolonged and fractionated right atrial endocardial electrograms are characteristic of paroxysmal atrial fibrillation (idiopathic or associated with sick sinus syndrome). The distribution of these abnormal atrial electrograms within the right atrium and the way it is related to the likelihood that patients with sick sinus syndrome will develop paroxysmal atrial fibrillation was studi...

INTRODUCTION AND OBJECTIVES The aim of this study was to determine the prognostic value of electrocardiography in hemodynamically stable patients with a diagnosis of acute symptomatic pulmonary embolism (PE). METHODS This prospective study included all hemodynamically stable outpatients who were diagnosed with PE at a university hospital. The electrocardiographic abnormalities investigated we...

The present study describes the clinical and electrophysiological characteristics of sustained bundle branch reentrant ventricular tachycardia treated with electrical ablation of the right bundle branch. Seven patients presented with syncopal episodes, and six of the seven had documented episodes of ventricular tachycardia. All patients had depressed left ventricular ejection fraction with card...

The antiarrhythmic effects of potassium canrenoate were examined in 20 closedchest, pentobarbital-anesthetized dogs with ouabain-induced ventricular tachycardia. In a group of 8 dogs, a mean dose of ouabain of 64.4 ± 3.7 /ig/kg induced sustained ventricular tachycardia. Subsequent administration of potassium canrenoate (30 mg/kg, iv) caused ventricular fibrillation in 1 dog and sinus tachycardi...

A 74-year-old male with severe, inotrope-dependent congestive heart failure (CHF) and previous episodes of slow ventricular tachycardia (VT) was evaluated for ongoing VT which persisted despite several attempts at ablation. The patient had a dual-chamber, biventricular Medtronic defibrillator programmed with a VT-1 zone of 500 ms and with ‘Onset’ as the only active discriminator. He had a histo...