PURPOSE: The Tofts models have long been regarded as a standard approach to tracer-kinetic analysis of DCE-MRI [1]. However, recent technological advances such as parallel imaging and higher field strengths have improved DCE-MRI data quality to a point where more complex models are required [2]. For tissues with a bidirectional exchange of tracer between intraand extravascular spaces, a number ...

Finding the causative genes for common diseases using SNP (Single Nucleotide Polymorphism) markers is now becoming a real challenge. Although traditional statistical SNP association tests exist, these tests could not explain the effects of SNP combinations or probable recombination histories from ancestral chromosomes. Haplotype analysis of disease associated site provides more powerful markers...

Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. There is good reason to believe that predictions from these different classes of algorithms could be used in conjunction to improve the quality of predictions. In this paper, we apply single layer networks and support vector machines on predictions from key algorithms. Furthermore, w...

Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. There is good reason to believe that predictions from these different classes of algorithms could be used in conjunction to improve the quality of predictions. In this paper, we apply single layer networks, rules sets and support vector machines on predictions from 12 key algorithms....