Let L be a bounded distributive lattice. For k 1, let Sk (L) be the lattice of k-ary functions on L with the congruence substitution property (Boolean functions); let S(L) be the lattice of all Boolean functions. The lattices that can arise as Sk (L) or S(L) for some bounded distributive lattice L are characterized in terms of their Priestley spaces of prime ideals. For bounded distributive lat...

This data paper contains information about the in vivo model for peritoneal implants used in the paper "Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells" (De Vlieghere et al., 2015) [1]. A double in vivo selection of SK-OV-3 Luc human ovarian cancer cell line was used to create SK-OV-3 Luc IP1 and SK-OV-3 Luc IP2 cell lin...

Human plasma contains a proteolytic enzyme precursor termed plasminogen (I) or profibrinolysin (2), which, upon activation by physical agents or specific bacterial kinases, is converted to plasmin (1) or fibrinolysin (2). Streptokinase (henceforth referred to as SK), an extracellular hemolytic streptococcal product, has been a commonly used activator for human plasminogen. Two mechanisms have b...

Early electrical activity and calcium influx regulate crucial aspects of neuronal development. Small-conductance calcium-activated potassium (SK) channels regulate action potential firing and shape calcium influx through feedback regulation in mature neurons. These functions, observed in the adult nervous system, make them ideal candidates to regulate activity- and calcium-dependent processes i...

The pharmacological properties of slow Ca(2+)-activated K(+) current (K(slow)) were investigated in mouse pancreatic beta-cells and islets to understand how K(slow) contributes to the control of islet bursting, [Ca(2+)](i) oscillations, and insulin secretion. K(slow) was insensitive to apamin or the K(ATP) channel inhibitor tolbutamide, but UCL 1684, a potent and selective nonpeptide SK channel...

“SK channels: an AFM and immunofluorecense study” Presented By: Krithika Abiraman Advisor: Dr. George Lykotrafitis Small-conductance calcium-activated potassium (SK) channels mediate a potassium conductance in the brain and are involved in synaptic plasticity, learning, and memory. SK channels exhibit a distinct subcellular localization that is crucial for their neuronal functions. However, the...

a Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac), University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada b Department of Physiology, Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON M5S 1A8, Canada c Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon,...

1. SK channels are small-conductance calcium-activated potassium channels that are widely expressed in neurons. The traditional view of the functional role of SK channels is in mediating one component of the after-hyperpolarization that follows action potentials. Calcium influx via voltage-gated calcium channels active during action potentials opens SK channels and the resultant hyperpolarizati...

Spore killer strains, found in Neurospora, provided the first recognized example of meiotic drive in fungi. In the present study, natural populations throughout the world were examined for the presence of killer strains and strains that are resistant to killing. In N. intermedia, Sk-2 and Sk-3 are present but are rare. Killer strains were found at only five sites, in Borneo, Java, and Papua New...

Small conductance Ca(2+)-activated potassium channels (SK channels) distributing in the nervous system play an important role in learning, memory and synaptic plasticity. Most pharmacological properties of them are determined by short-chain scorpion toxins. Different from most voltage-gated potassium channels and large-conductance Ca(2+)-activated potassium channels, SK channels are only inhibi...