Abstract Convolutional Neural Network (CNN) is a branch of deep learning which has been one popular methods in different applications, especially medical field. In this study, an optimized CNN model built using the random search optimization to classify seven types skin cancer, namely, basal cell carcinoma, melanoma, dermatofibroma, vascular lesion, melanocytic nevus, actinic keratosis and beni...

(UV) light-induced skin damage. On the other hand, overexposure to UV radiation can lead to a pathological increase in melanin production. Epidermal hyper-pigmentation results from the increased activity of melanogenic enzymes such as tyrosinase. Tyrosinase oxidizes the conversion of L-tyrosine to 3,4-dihydroxyphenylalanine (DOPA) and DOPA to DOPA quinone, which are the first two rate limiting ...

Hereditary equine regional dermal asthenia (HERDA) is an autosomal recessive skin disorder that has yet to be fully characterized. HERDA is predominately expressed in Quarter Horses, with the majority of these disseminating from elite cutting horse bloodlines, leading to the increased incidence of HERDA in recent years. Affected horses have loose, hyper-extensible, fragile skin and are frequent...

OBJECTIVE To determine the prevalence and pattern of skin disorders among female schoolchildren in primary and intermediate schools in Al-Khobar city, Eastern Saudi Arabia. METHODS This is a cross-sectional study conducted in Al-Khobar city, Kingdom of Saudi Arabia during the period from January-March 2003. It involved 2239 female schoolchildren randomly selected from 30 regular public and pr...

Background: Melasma is a common disorder of hyperpigmentation affecting millions of people worldwide. All the exact pathways to understand the complete pathogenesis of melasma is unknown. Aims: To determine the biophysical characteristics of melasma skin compared to the normal surrounding skin. Methods: Thirty-six patients with melasma were recruited in this case-control study. The subtype of m...

The transcription factor Ets1 is expressed at low levels in epidermal keratinocytes under physiological conditions, but is over-expressed in cutaneous squamous cell carcinoma (SCC). We previously showed that over-expression of Ets1 in differentiated keratinocytes of the skin leads to significant pro-tumorigenic alterations. Here, we further extend these studies by testing the effects of over-ex...

In this paper rst we dene the notions of positive implicativehyper MV -ideals of types 1,2,3 and 4 in hyper MV -algebras and we investigatethe relationship between of them . Then by some examples we show that thesenotions are not equivalent. Finally we give some relations between these notionsand the notions of (weak) hyper MV -ideals and (weak) hyper MV -deductivesystems of hyper MV -algebras.

In this paper, hyper-Fibonacci and hyper-Lucas polynomials are defined some of their algebraic combinatorial properties such as the recurrence relations, summation formulas, generating functions presented. addition, relationships between given.