aeroallergens continue to have a key role in the pathogenesis of asthma and allergic diseases and have recently received increased attention in medical research throughout the world. the prevalence of aeroallergens vary in different regions, depending on the type of climate. the aim of the present study was to determine prevalence of the sensitivity to aeroallergens among patients with asthma a...

Tumour necrosis factor (TNF) is a proinflammatory cytokine that increases human airway tissue responsiveness and is considered a candidate gene for asthma. Two common polymorphisms (LTalphaNcoI and TNFalpha-308) in the TNF gene complex were studied in 600 subjects from 131 Italian families with atopic asthmatic children. Skin prick test (SPT), total IgE levels, atopy (defined as increased IgE l...

Type I hypersensitivity is driven by allergen specific immunoglobulin E (sIgE) and thus sIgE represents a marker for modern allergy diagnosis. Recently, a rapid assay for the detection of sIgE, termed as (Allergy Lateral Flow Assay) ALFA, has been developed. The objective of our study is the evaluation of a scanner-based system for the semiquantitative interpretation of ALFA results. Agreement ...

BACKGROUND The clinical role of house dust mite (HDM) in atopic dermatitis (AD) is still controversial. OBJECTIVE The aim of the study is to assess the prevalence, clinical relevance and characteristics of adult-onset AD patients with positive skin prick tests (SPT) to mites. METHODS The case record forms of adult-onset AD patients who underwent SPT at the Skin Allergy Clinic, Siriraj Hospi...

Tumour necrosis factor (TNF) is a proinflammatory cytokine that increases human airway tissue responsiveness and is considered a candidate gene for asthma. Two common polymorphisms (LTáNcoI and TNFá-308) in the TNF gene complex were studied in 600 subjects from 131 Italian families with atopic asthmatic children. Skin prick test (SPT), total IgE levels, atopy (defined as increased IgE levels or...

background: the prevalence of allergic diseases has risen in the last decades. the objective of this study was to determine the common allergens in children via the skin prick test. methods: this cross-sectional study recruited 313 allergic children (4 months to 18 years old) referred to the asthma and allergy clinic of children’s medical center in tehran. a questionnaire containing demographic...

introduction: the diagnostic work-up of allergic rhinitis (ar) is first and foremost based on the combination of clinical history data and results of skin prick tests (spt). other tests, including specific ige measurement, nasal challenge, and, as a third option, component resolved diagnosis or basophil activation test, may be useful when the diagnosis is difficult because of polysensitization ...

AIMS To explore relations between exposure to fungal alpha-amylase and the risk of new work related respiratory symptoms or sensitisation. METHODS A prospective cohort study among 300 bakers and millers was followed up for a maximum of seven years. Exposure to alpha-amylase was estimated by air measurements and questionnaires and classified into three categories. Symptoms were recorded with a...

Background Allergic rhinitis is one of the most common types of rhinitis. Allergen avoidance is the most important way of preventing this disease. The present study is carried out to determine the frequency of common aeroallergens in patients with allergic rhinitis in Gorgan city by skin prick test (SPT) reactivity. Materials and Methods  In this cross-sectional study 270 patients referring t...

Methods 128 children with suspected CMA were undergone to CMFC (June/2007 to Feb/2014) and comprised two groups according to the result: negative test (passed, PG, n=100) and positive test (failed, FG, n=28). Both groups were analyzed regarding to age at first reaction, gender, nutritional status, breastfeeding, familial history of FA, symptoms reported, presence of asthma, allergic rhinitis or...