نتایج جستجو برای: skin substitutes
تعداد نتایج: 201103 فیلتر نتایج به سال:
Relevance. Despite scientific and technological progress improvement of treatment methods, providing assistance for thermal burns the skin remains a complex multicomponent problem. Extensive deep are not capable self-healing, therefore, over past century, autodermoplasty has become standard method treatment. However, shortage healthy tissues patient often does allow transplantation to be perfor...
OBJECTIVE To compare PermeaDerm to first temporary biosynthetic skin substitute (Biobrane, cleared by the Food and Drug Administration in 1979). METHODS Different temporary skin substitutes (Biobrane, PermeaDerm, and PermeaDerm derivatives) were tested for physical differences, impact on healing wounds, inflammatory response, and ability to allow adequate growth of dermal fibroblasts and mese...
This report of four patients (2 male, 2 female) presents preliminary results of treatment of chronic skin wounds with cultured skin substitutes prepared from allogeneic human skin cells and collagen substrates. The patients ranged in age from 64 to 73 years (mean: 67.25). The etiologies of their wounds were saphenous veinectomy, venous stasis, peripheral vascular disease, and venous stasis, wit...
There is a clinical need for skin substitutes to replace full-thickness skin loss. Our group has developed a bilayered skin substitute produced from the patient's own fibroblasts and keratinocytes referred to as Self-Assembled Skin Substitute (SASS). After cell isolation and expansion, the current time required to produce SASS is 45 days. We aimed to optimize the manufacturing process to standa...
Rapid coverage and epithelial closure of extensive burns remains a major requirement for patient recovery. Although many skin substitutes have been described, permanent regeneration of both epithelial and connective tissues after a single surgical application of a skin substitute has not become routine. To replace both dermal and epidermal skin, cultured skin substitutes (CSS) were prepared fro...
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