نتایج جستجو برای: small heat shock protein shsps
تعداد نتایج: 2156211 فیلتر نتایج به سال:
A lthough their better-known cousins, the Hsp70, Hsp90, and Cpn60 molecular chaperone families, have been the subjects of ever more detailed mechanistic scrutiny (1, 2), the small heat shock proteins (sHSPs) have remained mysterious and relatively understudied, even though they are ubiquitous and intimately linked to protein homeostasis and survival under stress conditions (3). There are severa...
Defective protein quality control (PQC) systems are implicated in multiple diseases. Molecular chaperones and co-chaperones play a central role in functioning PQC. Constant mechanical and metabolic stress in cardiomyocytes places great demand on the PQC system. Mutation and downregulation of the co-chaperone protein BCL-2-associated athanogene 3 (BAG3) are associated with cardiac myopathy and h...
recombinant human interferon alpha 2a (rhifn α -2a) production and cell growth were monitored in a set of genetically modified e. coli strains (msd1519, msd1520, msd 1521, msd 1522, msd 1523) producing rhifn α -2a. the growth was followed at od 600 nm, changes in cell physiology were detected by pyrolysis mass spectrometry (pyms) of cell biomass and recombinant protein production was determined...
Small heat shock proteins 9 and 10 (HSPB9 and HSPB10) are two testis-specific expressed sHsps. The objective of this study was to investigate the mRNA expression profile of HSPB9 and HSPB10 in goat testis among the different seasons, ages, and environmental temperatures. Allocation of the two sHsps was also performed by immunohistochemistry. The results showed that the transcript levels of HSPB...
Plant small heat shock proteins (sHSPs) are known to be important for environmental stress tolerance and involved in various developmental processes. In this study, two full-length cDNAs encoding sHSPs, designated JcHSP-1 and JcHSP-2, were identified and characterized from developing seeds of a promising biodiesel feedstock plant Jatropha curcas by expressed sequence tag (EST) sequencing of emb...
The dynamics of protein complexes are crucial for their function yet are challenging to study. Here, we present a nanoelectrospray (nESI) mass spectrometry (MS) approach capable of simultaneously providing structural and dynamical information for protein complexes. We investigate the properties of two small heat shock proteins (sHSPs) and find that these proteins exist as dodecamers composed of...
Dairy animals have a significant role in every country’s agricultural economy. Livestock is the major sub-sector of industry and value dairy products increasing globally. Under pathological circumstances heat shock proteins (HSPs) promote protein repair, folding, refolding misfolded peptides, possible breakdown irreparable proteins. Heat 27 (HSP27) member small family (sHSPs) also called HSPB1....
Both prokaryotes and eukaryotes tolerate different stress conditions (e.g., metabolic, environmental and pathophysiological stress) by up-regulating the expression of heat shock proteins (HSPs). These proteins are divided into six main families such as Hsp100, Hsp90, Hsp70, Hsp60, Hsp40 and small heat shock proteins (sHsps) based on their molecular weights (MW) and sequence homology [1, 2]. Amo...
Small heat shock proteins (sHSPs) are a diverse group of proteins and are highly abundant in plant species. Although majority of these sHSPs were shown to express specifically in seed, their potential function in seed physiology remains to be fully explored. Our proteomic analysis revealed that OsHSP18.2, a class II cytosolic HSP is an aging responsive protein as its abundance significantly inc...
Plantlets of Populus yunnanensis Dode were examined in a greenhouse for 48 h to analyze their physiological and proteomic responses to sustained heat, drought, and combined heat and drought. Compared with the application of a single stress, simultaneous treatment with both stresses damaged the plantlets more heavily. The plantlets experienced two apparent response stages under sustained heat an...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید