The present studies examined the mechanism of bicarbonate transport across basolateral membrane vesicles prepared from rabbit renal cortex. Isotopic sodium uptake was stimulated by bicarbonate when compared with gluconate (2.5 nmol/mg protein per 5 s versus 1.4 nmol/mg protein per 5 s), and this process was inhibited by disulfonic stilbenes. Imposition of an interiorpositive potassium diffusion...

DIFFERENCES IN CREATINE RETENTION AMONG THREE NUTRITIONAL FORMULATIONS OF ORAL CREATINE SUPPLEMENTS. Mike Greenwood, Richard Kreider, Conrad Earnest, Christopher Rasmussen, Anthony Almada. JEPonline. 2003;6(2):37-43. Previous research has indicated that creatine retention is influenced by intramuscular creatine concentration and extracellular concentrations of glucose and insulin. This study ex...

We attempted to determine the effect of extreme alkalemia induced by highdose sodium bicarbonate on the vasopressor effects of epinephrine during cardiopulmonary resuscitation (CPR). Subjects in this randomized, blinded study performed in a controlled laboratory environment were 12 mongrel dogs that had had a previous episode of CPR. Each dog underwent 3 minutes of ventricular fibrillation (VF)...

Butyric acid is detected in periodontal pockets and is thought to be involved in the initiation and progression of periodontal disease. We examined the effects of sodium bicarbonate on the butyric acid-induced epithelial cell damage. The human gingival carcinoma cell line Ca9-22 was cultured in medium that contained butyric acid with or without sodium bicarbonate. The viability of cells treated...

OBJECTIVE The aim of this experimental study was to investigate whether hypertonic saline or sodium bicarbonate administration prevented the development of cardiotoxicity in rats that received toxic doses of amitriptyline. METHOD Thirty-six Sprague Dawley rats were used in the study. The animals were divided into six groups. Group 1 received toxic doses of i.p. amitriptyline. Groups 2 and 3 t...

Pulmonary hypertension syndrome (PHS), commonly called ascites, is a costly metabolic disease occurring in rapid-growing chickens. Research has shown that dietary sources of energy (KHAJALI and FAHIMI, 2010) and protein (IZADINIA et al., 2010) have significant effects on pulmonary hypertensive response in broiler chickens. It has been suggested that rapid-growing broilers may be in the status o...

Phytase is traditionally supplemented into broiler diets between 300 and 600 phytase units (FTU)/kg. This supplementation releases phosphorus (P) from phytate in feed ingredients. The obvious benefit is the increase in available nutrients. Another benefit, when phytase is added to corn-soybean meal based diets, the production costs are reduced, leg abnormalities are minimized and bird growth ma...

1. Distal blockade by simultaneous administration of ethacrynic acid and chlorothiazide was performed in healthy subjects whose extracellular fluid was expanded by iso-osmotic sodium chloride or bicarbonate. The results obtained were compared with those from non-expanded subjects (Ardaillou & Fillastre, 1969). 2. By this technique urine approximates in composition to proximal tubular fluid and ...