UNLABELLED The use of (99m)Tc-sulfur colloid lymphoscintigraphy for the determination of lymph flow patterns from a tumor site and localization of the sentinel node has been widely adopted. However, the effects of multiple injections of the radiopharmaceutical can range from mild discomfort to pain. pH-adjusted lidocaine HCl coadministered with (99m)Tc-sulfur colloid presents a risk of introduc...

UNLABELLED (99m)Tc is currently produced by an aging fleet of nuclear reactors, which require enriched uranium and generate nuclear waste. We report the development of a comprehensive solution to produce (99m)Tc in sufficient quantities to supply a large urban area using a single medical cyclotron. METHODS A new target system was designed for (99m)Tc production. Target plates made of tantalum...

The aim of this study is to determine the contribution of neck and chest Tc-pertechnetate scan to the management of postoperative patients with suspicious metastatic differentiated thyroid cancer (DTC), particularly to the prediction of response to radioiodine (I) therapy. Just before I administration, a total of 184 postoperative DTC patients with stimulated serum thyroglobulin (ssTg) >10 ng/m...

A LeVeen peritoneo-venous shunt is placed for intractable ascites. Determination of obstruction site in the shunt tube is a difficult problem. We describe a simple nuclear medicine method using 111MBq (3mCi) of Technetium-99m labeled macro-aggregated albumin injected intraperitoneally.

Evaluation of Tc-99m red blood cell (RBC) SPECT in suspected hemangioma of the liver shows a high sensitivity and specificity when lesions are larger than 2 cm, and allows for the discrimination between hemangioma and other hepatic lesions. However, its major limitation arises with small size lesions. The accuracy of Tc-99m RBC SPECT in small suspected hemangiomas of the liver might improve the...

Tc-99m labeled RBC scintigraphy is commonly employed in the evaluation of acute gastrointestinal bleeding. On Tc-99m RBC studies gastrointestinal bleeding is seen as an initial focus of increased radiotracer activity that on subsequent images increases in intensity and changes position in a pattern that conforms to segments of bowel. We report a case of a patient with multiple episodes of hemat...

OBJECTIVES This study sought to examine the influence of time to reperfusion on myocardial salvage. BACKGROUND Major trials of reperfusion therapy for myocardial infarction (MI) have demonstrated improved outcome for patients achieving earlier reperfusion. However, some patients experience significant benefit despite delayed reperfusion. METHODS Fifty-five patients with a first anterior MI ...

A 41-year-old woman with rectal bleeding was referred to our department for gastrointestinal (GI) bleeding study. She was in early post-menstrual period and had stable vital signs. A GI bleeding study with Tc-99m SC revealed uterine blush in the pelvis. The shape of activity and quick fading excluded a GI bleeding. To rule out an intermittent bleeding, patient underwent a second bleeding study ...

ACR Appropriateness Criteria 1 Urinary Tract Infection–Child American College of Radiology ACR Appropriateness Criteria Urinary Tract Infection–Child Variant 1: Age <2 months, first febrile urinary tract infection. Radiologic Procedure Rating Comments RRL* US kidneys and bladder 9 O Voiding cystourethrography 6 Consider this procedure in boys and in the presence of sonographic abnormality. ☢☢ T...

BACKGROUND Macrophages represent a critical cell type in host defense, development and homeostasis. The ability to image non-invasively pro-inflammatory macrophage infiltrate into a transplanted organ may provide an additional tool for the monitoring of the immune response of the recipient against the donor graft. We therefore decided to image in vivo sialoadhesin (Sn, Siglec 1 or CD169) using ...