نتایج جستجو برای: soluble activators
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The majority of bacterial promoters are regulated by at least two transcription factors. Many of these promoters are regulated by two activators, with expression being co-dependent on the activity of both activators [l] . At most of these promoters, one of the activators responds to a ‘global’ regulatory signal whilst the other responds to a ‘specific’ signal. For example, transcription initiat...
DNA sequences that determine transcriptional regulation of a typical eukaryotic gene consist of a core promoter, which serves as a binding site for the GTF TFIID, and regulatory promoter or enhancer sequences, which bind transcriptional activators. The RNA polymerase II transcription machinery consists of over 50 proteins which are thought to bind to the core promoter in as few as two steps: bi...
Nuclear hormone receptors (NRs) activate transcription by binding to specific enhancer elements associated with target genes. Transcriptional activation is accomplished with the help of complexes of co-activator proteins that bind to NRs. p160 co-activators, a family of three related 160 kDa proteins, serve as primary co-activators by binding directly to NRs and recruiting additional secondary ...
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