background: the gail model has been widely used for estimation of absolute risk of breast cancer development. the original model and most of the validation studies have been performed among western populations and controversial results have been reported regarding the applicability of this model in asian populations. our aim was to investigate the performance of this model in iranian women. met...

Cocrystal Content N. A. Heron, Y. Tian, D. S. Jones, G. P. Andrews Queen's University of Belfast Purpose The solubility of a drug within the gastrointestinal tract has a direct impact upon its oral bioavailability. Numerous strategies have successfully enhanced drug solubility; however, these approaches are unreliable as long term solutions due to physical instability of the drug form. Crystal ...

the use of l1 in language classroom has been traditionally repressed by applied linguists. however, in recent years, it is believed that switching to l1 can be considered a pedagogical instrument by teachers rather than a heterodox. consequently, this two-phase study was an attempt to investigate the functions that are fulfilled by efl teachers through their use of l1. in the first phase (i.e.,...

conclusions the evaluation of the questionnaire for identifying the individuals in the risk of addiction showed that the questionnaire benefits from appropriate validity and reliability. therefore, it can be used in preventive fields and research. moreover, by illuminating interpersonal factors that are effective in drug abuse, proper strategies can be used to prevent drug addiction. results in...

In this study, a dispersive liquid–liquid microextraction along with back-extraction step (DLLME-BE) has been developed for the determination of thre antidepressant drugs (citalopram, sertraline, and venlafaxine) in biological samples prior to HPLC-UV. Briefly, method involved two main steps: first, deep eutectic solvent (DES) composed tetrabutylammonium bromide (TBABr as agent) 1-dodecanol (as...

ABSTRACT: The foremost intention of present research was the preparation and assessment mouth dissolving formulation Rivaroxaban its validation. During work, this tablet formulated by straight compression technique means Cros-carmellose sodium Sodium starch glycolate as super-disintegrants (concentration 2, 4, 6%) Avicel 102 a binder. preparations were exposed to different consideration paramet...

Variational based solvation models of biomolecules with smooth interface have drawn attentions in the past decade since they been developed as an efficient and reliable representation solute-solvent interfaces framework implicit solvent models. This work aims at providing solid mathematical supports for a promising geometric flow computational model (GFBSS) its involved treatments. For this pur...

background: to determine the atmospheric contamination by pesticides, conducting laboratory studies is necessary before operating field studies. the aim of this research study was to develop an analytical method to sample and simultaneously determine airborne amitraz and its metabolite. methods: a modified fritted impinger with acetonitrile as the liquid sorbent was used in order to study the a...

a sensitive fluorometric method for the determination of deferiprone (dfp) based on the formation of a luminescent complex with tb3+ ions in aqueous solutions is reported. the maximum excitation and emission wavelengths were 295 and 545 nm, respectively. the effects of various factors on the luminescence intensity of the system were investigated and optimized, then under the optimum conditions,...