OBJECTIVE To determine the value of placental volume measured by 3D ultrasound at 11-13 weeks' gestation in combination with maternal characteristics and serum pregnancy-associated plasma protein-A (PAPP-A) in the prediction of small and large for gestational age (SGA and LGA) neonates. METHODS Maternal serum PAPP-A and placental volume were measured at 11-13 weeks in 3,104 singleton pregnanc...

The main classical branches of celiac trunk (CT) are the common hepatic artery (CHA), the left gastric artery (LGA) and the splenic artery (SA). During the educational dissections in a 62-year-old male cadaver a rare variation, the gastroduodenal-splenic trunk (GDST), was observed. GDST divided into SA and gastroduodenal artery (GDA). LGA and accessory left hepatic artery (ALHA) arose directly ...

The study assesses the impact of last major flood disaster in Ibadan on vulnerable groups (the poor, elderly, children and physically challenged). It investigates how HHs have responded to post-disaster events. finds that from 56% affected buildings suffered temporary displacement 207 (7.4%) were abandoned with South-West LGA recording highest cases abandonment (23%). There exists a positive co...

We use the generalized singular value decomposition (GSVD), formulated as a comparative spectral decomposition, to model patient-matched grades III and II, i.e., lower-grade astrocytoma (LGA) brain tumor and normal DNA copy-number profiles. A genome-wide tumor-exclusive pattern of DNA copy-number alterations (CNAs) is revealed, encompassed in that previously uncovered in glioblastoma (GBM), i.e...

OBJECTIVE To develop a prediction model for term infants born large for gestational age (LGA) by customised birthweight centiles. METHODS International prospective cohort of nulliparous women with singleton pregnancy recruited to the Screening for Pregnancy Endpoints (SCOPE) study. LGA was defined as birthweight above the 90th customised centile, including adjustment for parity, ethnicity, ma...

OBJECTIVE Adipose tissue dysfunction, characterized by dysregulation of adipokines production and/or secretion, has been implicated in the pathophysiology of type-2 diabetes mellitus, a metabolic complication closely related to gestational diabetes mellitus (GDM). Recently, an association between circulating maternal visfatin, a novel adipokine with metabolic and immunoregulatory properties, an...

BACKGROUND N-acetylcysteine (NAC) has been suggested to prevent relapse to cocaine seeking. However, the psychological processes underlying its potential therapeutic benefit remain largely unknown. METHODS We investigated the hallmark features of addiction that were influenced by chronic NAC treatment in rats given extended access to cocaine: escalation, motivation, self-imposed abstinence in...

We use Brownian motion ideas to study Schriidinger operators H = +A + V on Lp(R”). In particular: (a) We prove that limt+m t-l In /I e&H j111.9 is p-independent for a very large class of V’s where 11 A ll,,,n = norm of A as an operator from L’ to L”. (b) For Y > 3 and V E LY/~--E n L”Ip+c, we show that sup jl eetH Ilm,m -: (D if and only if H has no negative eigenvalues or zero energy resonance...

Purpose This research seeks to understand the potential impact investors from government responses climate change risk, as reflected in changes planning processes made after significant weather events. Design/methodology/approach The examines land within a select local authority (“LGA”) area following four events, order identify any made, and on future development proposals. LGA selected is Cen...

Macrosomia, usually defined as infant birth weight of ?4000 g, does not consider gestational age, sex, or country/region-specific differences in mean and maternal body weight. This issue is particularly relevant for Asia, where 60% the world's population lives, due to variations size weights across populations. Large age (LGA), > 90th centile, a more sensitive measure it considers though depend...