nodules that reside within the dermis and frequently demonstrate epidermal attachment. Multifocal lobules of varying size and shape exhibit peripheral palisading and central haphazard array of cells.The entire tumor demonstrates an expansile growth pattern. Cystic degeneration or central necrosis may be prominent. Although similar to the nodular variant, micronodular basal cell carcinoma is com...

BACKGROUND Women living with HIV (WLWH) are at increased risk of invasive cervical cancer (ICC). International HIV guidelines suggest cervical screening twice the first year after HIV diagnosis and thereafter annually. Adherence to the HIV cervical screening program in Denmark is unknown. METHODS We studied women from a population-based, nationwide HIV cohort in Denmark and a cohort of age-ma...

Infiltrating lobular carcinoma (ILC) and infiltrating ductal carcinoma (IDC) are distinguished by their histopathological appearance. However, little is known about the differences in genetic changes between lobular cancers and ductal cancers. We used comparative genomic hybridization (CGH) and compared aberrations in 19 ILCs and 46 IDCs. The total number of aberrations was lower in ILC than in...

We report two rare cases of breast cancer in men treated with modified radical mastectomy. The patients were aged 67 and 45 years at the time of diagnosis. Tumor sizes were 2 cm and 8 cm in the older and younger patient, respectively. The histopathologic diagnosis was infiltrating ductal carcinoma in the first patient and infiltrating papillary carcinoma in the second patient. Immunohistochemic...

Guglielmo Ronco, MD, of the Center for Cancer Epidemiology and Prevention in Turin, Italy, and colleagues pooled more than 175,000 women, aged 20 to 64, and followed them for a median of 6.5 years. The four trials used were from England (ARTISTIC), Italy (NTCC), the Netherlands (POBASCAM), and Sweden (SWEDESCREEN). A total of 107 patients had invasive cervical cancer using cancer registries and...

OBJECTIVE The age-specific incidence rate curve for breast carcinoma overall increases rapidly until age 50 years, and then continues to increase at a slower rate for older women. In this analysis, our objective was to compare age-specific incidence rate patterns for different morphologic types of breast carcinoma. MATERIALS AND METHODS We analyzed age-specific incidence rate curves by histop...

Basal cell carcinoma (BCC) is one of the most common cutaneous malignancies worldwide. Reports BCC on non-exposed areas are relatively uncommon. In our study we present case a male patient with in scrotum, since 3 years, successfully treated wide local excision. Histopathological examination confirms infiltrating BCC. Our objective to remind specialists possibility scrotal when encountering les...

Malignant mesothelioma is an uncommon tumor with strong association with asbestos exposure. Few cases of malignant pleural mesothelioma metastatic to the female breast have been reported. Herein, we presented, for the first time, a case of locally infiltrating malignant pleural mesothelioma forming a mass in the breast of a male as the first pathologically confirmed manifestation of the disease...

BACKGROUND Breast cancer is the most frequent malignant tumour to metastasize into the gastrointestinal tract in female and is second only to malignant melanoma. Nevertheless gastrointestinal metastases arising from breast cancer are quite rare. The upper gastrointestinal tract is more frequently involved and lobular infiltrating carcinoma has a greater predilection compared to the ductal type....

BACKGROUND Invasive lobular carcinoma (ILC) is the second most common histological type of invasive breast carcinoma, preceded only by infiltrating ductal carcinoma, which has clinical, biological and molecular distinctions. These distinctions imply a different metastatic behavior between the histology of these 2 types of breast cancer. CASE PRESENTATION We report the case of a 51-year-old wo...