Mouse fibroblasts, deficient in DNA polymerase ß (ß-pol), are hypersensitive to monofunctional DNA methylating agents such as methyl methanesulfonate (MMS). Both wild-type, and in particular repair deficient ßpol null cells, are highly sensitized to the cytotoxic effects of MMS by 4-amino-1,8naphthalimide (4-AN), an inhibitor of poly(ADP-ribose) polymerase (PARP) activity. Experiments with sync...

The searches for classical Dirac Magnetic Monopoles (MMs) at accelerators, for GUT superheavy MMs in the penetrating cosmic radiation and for Intermediate Mass MMs at high altitudes are discussed. Also the searches for nuclearites and Q-balls are considered.

The searches for classical Dirac Magnetic Monopoles (MMs) at accelerators, for GUT superheavy MMs in the penetrating cosmic radiation and for Intermediate Mass MMs at high altitudes are discussed. Also the searches for nuclearites and Q-balls are considered.

Bacillus subtilis was not inactivated and was able to replicate even though approximately 3 X 104 methyl groups added by methyl methanesulfonate (MMS) were bound to the deoxyribonucleic acid (DNA) of each organism. No significant loss of methyl groups from the DNA occurred for several generations upon incubation of methylated wild-type or MMS-sensitive cells. Single-strand breaks were not obser...

Mohs micrographic surgery (MMS) is the gold standard for the excision of locally invasive cutaneous malignancies in human dermatological surgery. Using a unique horizontal sectioning technique, MMS enables 100% surgical margin assessment and provides the lowest recurrence rates for locally invasive tumours. The purposes of this preliminary study were to explore the feasibility of application of...

The Manufacturing Message Specification (MMS) is the main application protocol of the MAP communication standard architecture. MMS covers the most important functions needed in manufacturing applications. It was initially designed to rely on an ISO protocol stack, but the OSI layering allows to consider MMS by itself, independently of its standard profile. As Internet protocols are wide spread ...

The motorized mobility scooter (MMS) provides considerable benefits to patients with mobility limitations. Nevertheless, safety concerns related to MMS use are an issue. With increased use because of increased life expectancy and chronic illness, there are a growing number of reports of MMS-related injuries, ranging from lacerations and contusions to fatalities. Comorbidities may also exacerbat...

BACKGROUND Early recognition is the most important intervention to improve melanoma prognosis. OBJECTIVE To report the value of dermoscopy and digital dermoscopy in the clinical diagnosis of malignant melanoma (MM). METHODS Retrospective analysis of 99 consecutive primary MMs diagnosed between 2010 and 2013. The MMs were divided into 3 groups: 1) the MM was the reason for consultation (MMC)...

Kinetic Alfvén waves (KAWs), with a strong parallel disturbed electric field, play an important role in the energy transport and particle acceleration magnetotail. Based on high-resolution observations of Magnetospheric Multiscale (MMS) mission, we present detailed process electrons by KAWs plasma sheet boundary layer (PSBL). MMS observed electromagnetic disturbances carrying field amplitude up...

In this study, we investigated the antipsychotic-like effect of methanolic extract of Mitragyna speciosa leaf (MMS) using in vivo and ex vivo studies. In vivo studies comprised of apomorphine-induced climbing behavior, haloperidol-induced catalepsy, and ketamine-induced social withdrawal tests in mice whereas the ex vivo study was conducted utilizing isolated rat vas deferens preparation. Acute...