Objectives: One of the most common and disabling complications that affects individuals with spinal cord injury is spasticity. The purpose of this study is to compare the effect of agonist and antagonist electrical stimulations on triceps surae muscle spasticity in patients with spinal cord injury. Methods: A total of 30 subjects with spinal cord injury were considered for the study. They were...

it has been shown that the immunophilin ligands have the special advantage in spinal cord repair. in this study, the effects of cyclosporine a (csa) on functional recovery and histological outcome were evaluated following spinal cord injury in rats. after spinal cord hemisection in thirty six adult female sprague-dawley rats (200- 250 g), treatment groups received csa (2.5 mg/kg i.p.) at 15min ...

Introduction: Spinal cord injuries (SCI) lead to permanent irreversible functional deficits.  Poor prognosis of patients is the motivation of searching a treatment for the chronic injury.  Planting stem cells provides us with a promising strategy. In the meanwhile, the use of olfactory ensheathing cells (OECs) has shown very good results.  This study aims at evaluating the effe...

objectives: although for those spinal cord injury (sci) patients with paralysis of the legs but not at arms, the primary means of mobility post injury is the manual wheelchair, there are many physiological and psychological advantages to standing and walking, such as improvement in respiratory function, lower limb weight bearing and preventing osteoporosis, pressure sores prevention etc. high m...

background: bone marrow stromal cells (bmsc) have been successfully employed for movement deficit recovery in spinal cord injury (sci) rat models. one of the unsettled problems in cell transplantation is the relative high proportion of cell death, specifically after neural differentiation. according to our previous studies, p75 receptor, known as the death receptor, is only expressed in bmsc in...

this descriptive study was aimed to identify how provided nursing care related to physical problems caused by traction and cast in patients with fracture and dislocation in cervical spinal cord in educational hospitals of tehran university of medical sciences. samples, including 46 patients were recruited from neurosurgery and orthopedic wards, and also from neurosurgical intensive care units d...

spinal cord injury (sci)-induced systemic inflammatory response affects multiple organs outside the spi­nal cord. treatment options for such complications are lacking. valproic acid (vpa) is a histone deacetylase inhibitor, acting directly at the level of gene transcription by inhibiting histone deacetylation and making transcription sites more accessible. acetylation of histones is critical to...

the purpose of this study was to shed light on the identification of themes and sub-themes of the quality of life (qol) in iranian veterans with spinal cord injury (sci). studies have reported decreased qol in sci patients which encompass all aspects of their life. little is known about qol in sci veterans from iran. the aim of this qualitative study was to identify related aspects of such pati...

prior animal models have shown that rats sustaining 3-second immediate spinal cord compression had significantly better functional recovery and smaller lesion volumes than rats subjected to compression times of 1 hour, 6 hours, 3 weeks, and 10 weeks after spinal cord injury. we compare locomotor rating scales and spinal cord histopathology after 3 seconds and 10 minute compression times. . ten ...