Context Degenerative lumbar spinal stenosis is a common cause of low back and leg pain in older individuals. The evidence supporting non-surgical treatments, including oral medications, physical treatments and spinal injections, is limited. Despite the lack of strong evidence supporting the use of epidural steroid injections (ESIs) for lumbar spinal stenosis, their use has increased dramaticall...

Systematic literature review. To review the evidence from high-quality studies regarding the treatment of neuropathic pain originating specifically from spinal disorders. In general, treatment guidelines for neuropathic pain cover all its various causes, including medical disease, peripheral neuropathy, and cancer. However, the natural history of neuropathic pain originating from spinal disorde...

Surgical decompression has been considered the gold standard for the symptomatic spinal stenotic patient. Thirty thousand decompressive procedures are performed annually and this number is expected to increase as the American population ages. Options are limited for the stenotic patient classified as a "poor surgical risk". Furthermore review of the literature indicates mixed results even in op...

As the population ages, more elderly patients suffer from spinal stenosis requiring lumbar fusion. However, there are few and conflicting results regarding the clinical outcome of lumbar fusion. The purpose of this study is to evaluate the safety and efficiency of posterior lumbar interbody fusion (PLIF) in over 75-year-old patients and analyze the relative effectiveness of lumbar spinal fusion...

Two collagen type IX gene polymorphisms that introduce a tryptophan residue into the protein's triple-helical domain have been linked to an increased risk of lumbar disc disease. To determine whether a particular subset of symptomatic lumbar disease is specifically associated with these polymorphisms, we performed a prospective case-control study of 107 patients who underwent surgery of the lum...

BACKGROUND Poorer postoperative outcome is suggested after repairing surgery in diabetic patients with lumbar spinal stenosis in comparison with nondiabetic patients. The present study aimed to compare the clinical outcome of surgery for lumbar spinal stenosis and diabetic and nondiabetic patients to highlight the effect of diabetes on prognosis of this surgical procedure. METHODS This prospe...

RATIONALE Hypertrophy of posterior longitudinal ligament (HPLL) at C1-2 level accompanied with lower cervical spinal stenosis is rare in clinic. No reports have described HPLL at C1-2 level accompanied with lower cervical spinal stenosis treated by posterior decompression, combined with internal fixation in 1 stage. PATIENT CONCERNS A 70-year-old Chinese female complained of numbness and para...

Spondylotic degeneration can manifest as tandem (concurrent) cervical and lumbar spinal stenosis. The primary manifestations include neurogenic claudication, gait disturbance and a mixture of findings of myelopathy and polyradiculopathy in both the upper and lower extremities. The purpose of this retrospective study was to report the existence and management of tandem (concurrent) cervical and ...