In its report, the SPC Review Panel has highlighted that the construction of a 4 MW SPL has to be motivated by the needs of a well-defined and approved physics programme, and that it should be compared with a Rapid Cycling Synchrotron (RCS) when considering only the needs of LHC. This report is meant to answer these remarks by describing the version of the SPL that would be built for the needs ...

the most accepted method of secondary prophylaxis in rheumatic fever (rf) has been an injection of 1,200,000 units of benzathine penicillin g (bpg) every 4 weeks, but recurrences have been reported in some patients despite such a prophylaxis program. the who recommended bpg injections every 3 weeks in high risk patients and situations due to some published data in favor of inadequacy of once ev...

The decision of ectodermal cells to adopt the sensory organ precursor fate in Drosophila is controlled by two classes of basic-helix-loop-helix transcription factors: the proneural Ac and Sc activators promote neural fate, whereas the E(spl) repressors suppress it. We show here that E(spl) proteins m7 and mgamma are potent inhibitors of neural fate, even in the presence of excess Sc activity an...

OBJECTIVES This study aimed (1) to investigate music theory teachers' professional and extra-professional vocal loading and background noise exposure, (2) to determine the correlation between vocal loading and background noise, and (3) to determine the correlation between vocal loading and self-evaluation data. METHODS Using voice dosimetry, 13 music theory teachers were monitored for one wor...

We used a pair of hydrophones to monitor sound pressure levels (SPL, dB re 1 μPa) and frequency spectra of ambient sounds in Haro Strait during 18 months (April 2004 November 2005). Half-hour average SPL in the broad frequency band 0.1-15 kHz ranges from minimum (background) levels of 95 dB to maximum levels of 130 dB. The average SPL over 17 months is 115 dB. The broadband sound field is domin...

Single photon lidar (SPL) is an innovative technology for rapid forest structure and terrain characterization over large areas. Here, we evaluate data from an SPL instrument - the High Resolution Quantum Lidar System (HRQLS) that was used to map the entirety of Garrett County in Maryland, USA (1700 km(2)). We develop novel approaches to filter solar noise to enable the derivation of forest cano...

To determine drug-induced hyperfunction of marmoset thyroids due to inhibition of synthesis or enhancement of metabolic elimination of thyroid hormones, males were orally administered 10 and 30 mg/kg/day methimazole (MMI), 30 and 100 mg/kg/day spironolactone (SPL), or 50 mg/kg/day phenobarbital (PB) for 4 weeks. MMI caused marked hypertrophy of follicular epithelial cells in accordance with a s...

BACKGROUND The evaluation of solitary pulmonary lesions (SPL) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis (TB) is endemic. Data on ultrathin bronchoscopy (UB) for this purpose is limited. To evaluate feasibility and safety of UB compared to SB for diagnosis of SPL in a TB endemic region. METHODS In this prospective rand...

Enhancer of split (E(spl)), one of the neurogenic loci of Drosophila, is uncovered by the deletion Df(3R)E(spl)(R-B251) with breakpoints at 96F8 and 96F13. We describe here the results of a genetic analysis of this chromosomal interval. Thirty-one mutations in genes of this region were recovered during various programs of mutagenesis. In addition, we included the spontaneous mutations E(spl)(D)...

Self-paced learning (SPL) is a new methodology that simulates the learning principle of humans/animals to start learning easier aspects of a learning task, and then gradually take more complex examples into training. This new-coming learning regime has been empirically substantiated to be effective in various computer vision and pattern recognition tasks. Recently, it has been proved that the S...