Mongolia has high prevalence of H. pylori infection and gastric cancer. Early detection eradication can prevent the progression atrophy we reduce incidence cancer in our country. A Kyoto classification score 2 or more indicates a Endoscopic 4 might indicate risk. In this study compared consistency between advanced early cancer, grade dysplasia low-grade This is retrospective that included patie...

Current research highlighted the importance to recognize feasible biomarkers for early diagnoses and treatment in oral cancer. Our study analyzed expression spatial distribution of ALDH1A1, FGFR2, caspase-3, CD44 Oral Squamous Cell Carcinoma (OSCC) leukoplakia with without mucosal dysplasia. Paraffin-embedded samples OSCC (n=5), (n=5) dysplasia obtained by incisional biopsies were processed usi...

Since the original description by Taylor, the term focal cortical dysplasia has been used to refer to a wide range of alterations of the cortical mantle. More recently, these conditions have been described from neuroimaging, neuropathological and genetic standpoints, generating several classifications. It is widely recognized that these classifications are unsatisfactory. We propose a simplifie...

This study represents a multiplex cytokine analysis of serum from a 10-month randomized, controlled trial of 238 subjects that investigated the effects of selenomethionine and/or celecoxib in subjects with mild or moderate esophageal squamous dysplasia. The original chemoprevention study found that, among those with mild dysplasia, selenomethionine treatment favorably altered dysplasia grade. T...

The aim of the study was to evaluate the justification of Croatian modification of Bethesda classification after thirteen years of its application, answering the question if the subclassification of high-grade squamous intraepithelial lesion (HSIL) into cervical intraepithelial lesion (CIN) grade 2 (CIN2) and grade 3 (CIN3) is cytologically real and clinically justified. The retrospective study...

Cortical dysplasia accounts for at least 14% of epilepsy cases, and is mostly seen in children. However, the understanding of molecular mechanisms and pathogenesis underlying cortical dysplasia is limited. The aim of this cross-sectional study is to identify potential key molecules in the mechanisms of cortical dysplasia by screening the proteins expressed in brain tissues of childhood cortical...

OBJECTIVES The objectives were to determine the prevalence of laryngeal dysplasia and associated human papilloma virus (HPV) subtypes in adult patients, 18 years or older, suffering from laryngeal papillomatosis at a tertiary care institution. STUDY DESIGN Retrospective cohort study. METHODS Patients with biopsy proven laryngeal papillomatosis were identified via chart review. All available...

OBJECTIVE Absence of dysplasia in the excised specimen following loop electrosurgical excision procedure (LEEP) for treatment of cervical intraepithelial neoplasia (CIN) 2/3 is an occasional finding of uncertain clinical significance. We evaluated several factors including age, liquid-based Pap (LBP) test, human papillomavirus (HPV) load before treatment, and HPV typing as predictors for absenc...

The natural history of gastric epithelial dysplasia and its relation to gastric cancer are ill defined. A consecutive series of 40 patients with an initial diagnosis of gastric epithelial dysplasia based on examination of endoscopic biopsies has been reviewed to determine the clinical outcome and to evaluate a two tier histological grading system as a predictor of the risk of cancer. On review,...

Ectodermal Dysplasia is a hereditary disorder commonly associated with trichodysplasia (abnormal hair), onchodysplasia nails), dyshidrosis or missing sweat glands) and abnormal dentition. Due to ectodermal dysplasia, for missing, abnormally shaped, mal-positioned teeth, wide range of prosthetic options are available oral rehabilitation. This case report represents prosthodontic rehabilitation c...