The purpose of this study is to develop non-destructive methods to determine the drug content of suppositories using near-infrared (NIR) spectrometry and X-ray computed tomography (XCT). The suppository samples (acetaminophen content: 0, 100, 200, 300, 400 and 500 mg/suppository) consisted of acetaminophen powder and hard fat. NIR spectra of 18 standard suppository samples were recorded, and th...

Images captured by wide-angle cameras show barrel type spatial (or radial lens) distortion due to wide-angle configuration of the camera lens where image regions farther from the center are compressed in a nonlinear fashion. The radial lens distortion correction technique based on least squares estimation corrects a distorted image by expanding it nonlinearly so that straight lines in the objec...