Causes of the progression periodontitis such as an imbalance between immune response by host release inflammatory mediators in oral pathogenic dysbiotic biofilm have been identified. New insights on specific cell signaling pathways that appear during attracted attention researchers study new personalised approaches for treatment periodontitis. The gold standard non-surgical therapy involves rem...

introduction: deep periodontal pockets pose a great challenge for nonsurgical periodontal treatment. scaling and root planing (srp) alone may not suffice in cases where surgical therapy cannot be undertaken. various recent studies have suggested the use of antimicrobial photodynamic therapy (apdt) for the management of periodontal infections. the aim of this study was to evaluate the effects of...

The primary goal of periodontal therapy is the removal of supra and subgingival bacterial deposits by mechanical debridement consisting in scaling and root-planing (SRP) using manual or power-driven instruments. The complete removal of bacteria and their toxins from periodontal pockets is not always achieved with conventional mechanical treatment. The use of lasers as an adjunctive therapy for ...

BACKGROUND Probiotics are living microorganisms that provide beneficial effects for the host when administered in proper quantities. The aim of this double-masked placebo-controlled parallel-arm randomized clinical trial is to evaluate the clinical effects of a Lactobacillus rhamnosus SP1-containing probiotic sachet as an adjunct to non-surgical therapy. METHODS Twenty-eight systemically heal...

BACKGROUND The treatment of periodontitis begins with a non-surgical phase that includes scaling and root planing(SRP) and on occasion the use of systemic antibiotics. The goal was to systematically evaluate in systemic healthy adults the effect of the concomitant administration of amoxicillin (amx) and metronidazole (met) adjunctive to SRP compared to SRP alone. METHODS The PubMed-MEDLINE, C...

BACKGROUND The treatment of aggressive periodontitis has always presented a challenge for clinicians, but there are no established protocols and guidelines for the efficient control of the disease. METHODS Ten patients with a clinical diagnosis of aggressive periodontitis were treated in a split-mouth design study to either photodynamic therapy (PDT) using a laser source with a wavelength of ...

PURPOSE Locally delivered, controlled-release antimicrobials have long been available in dentistry. Their utilization in routine clinical practice, however, has been slow, perhaps because of concerns about clinical benefits or costs or possibly due to a lack of understanding of their efficacy or proper use. In this paper the evidence regarding locally delivered, controlled-released antimicrobia...

Background and Aim: Reducing the number of pathogenic microorganisms can contribute to reducing the incidence and epidemiology of periodontal diseases. This study aimed to evaluate the clinical effects of Ardox-X active oxygen-containing toothpaste on periodontal indices in patients with at least 1 to 2 implants. Materials and Methods: In this crossover randomized clinical trial, 30 subjects w...

BACKGROUND Aggressive periodontitis is a specific form of periodontal disease that is characterized by rapid attachment loss and bone destruction. Cytokine profiles are of considerable value when studying disease course during treatment. The aim of this trial was to investigate cytokine levels in the gingival crevicular fluid (GCF) of patients with aggressive periodontitis, after treatment with...

In this study, the clinical efficacies of systemic doxycycline (SD) and local doxycycline (LD) in the treatment of chronic periodontitis were compared. Forty-five patients were studied in 3 main groups with 5 treatments: SD alone, SD+scaling-root planing (SD+SRP), LD alone, LD+SRP and SRP alone. Antibiotic-treated patients were given doxycycline treatment alone in 1 quadrant of their upper jaws...