Recent technical advances in positron emission tomography/magnetic resonance imaging (PET/MRI) technology allow much improved time-of-flight (TOF) and regularized iterative PET reconstruction regularized iterative reconstruction (RIR) algorithms. We evaluated the effect of TOF and RIR on standardized uptake values (maximum and peak SUV [SUVmax and SUVpeak]) and their metabolic tumor volume depe...

UNLABELLED PET/CT with the glucose analog (18)F-FDG has several potential applications for monitoring tumor response to therapy in patients with non-small cell lung cancer (NSCLC). A prerequisite for many of these applications is detailed knowledge of the repeatability of quantitative parameters derived from (18)F-FDG PET/CT studies. METHODS The repeatability of the (18)F-FDG signal was evalu...

BACKGROUND The aim of this study was to determine the value of 18F-FDG uptake on screening PET/CT images for the prediction of Helicobacter pylori (H. pylori) infection and chronic atrophic gastritis. METHODS Among subjects who underwent 18F-FDG PET/CT for cancer screening from April 2005 to November 2015, PET/CT images were analyzed in 88 subjects who had gastrointestinal fiberscopy within 6...

OBJECTIVE The aim of the present study was to evaluate prognostic values of pre-treatment fluorine-18 fludeoxyglucose (18F-FDG) positron emission tomography (PET) parameters for predicting the distant metastasis (DM) of nasopharyngeal cancer. METHODS 73 patients diagnosed with nasopharyngeal cancer with regional lymph node (LN) involvement, who underwent pre-treatment 18F-FDG PET evaluation b...

This article discusses the value of 18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma. 18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUVmax and SUVpeak), metaboli...

Purpose: In longitudinal oncological and brain PET/CT studies it is important to understand the repeatability of quantitative PET metrics in order to assess change in tracer uptake or binding. The present studies were performed in order to assess the aspects of PET/CT repeatability related to reconstruction settings, analysis methods, scan duration (or image noise) and position in the field of ...

BACKGROUND Although quantitative analysis using standardized uptake value (SUV) becomes realistic in clinical single-photon emission computed tomography/computed tomography (SPECT/CT) imaging, reconstruction parameter settings can deliver different quantitative results among different SPECT/CT systems. This study aims to propose a use of the digital reference object (DRO), which is a National E...

The aim of this study was to investigate the relationship between standardized uptake value (SUV), obtained from [18F]fluorodeoxyglucose positron emission tomography (FDG PET), and treatment response and survival of inoperable NSCLC patients treated with high dose radiotherapy. Fifty-one patients were included, recording stage, performance, weight loss, tumour volume, histology, lymph node invo...

Background: Evaluating the potential role of standardized uptake value (SUV) in patients with locally advanced, non-metastased, high-grade, extremity soft tissue sarcoma. Methods: Thirteen patients scheduled for hyperthermic isolated limb perfusion (ILP), referred for a 18F-Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET)-scan were eligible. The SUV in the sarcoma lesion was calculat...

Purpose The aim of this retrospective study was to determine, at baseline, the prognostic value of different FDG-PET/CT quantitative parameters in a homogenous Ewing Sarcoma Family of Tumors (ESFT) adult population, compared with clinically relevant prognostic factors. Methods Adult patients from 3 oncological centers, all with proved ESFT, were retrospectively included. Quantitative FDG-PET/...