A methicillin-resistant mecB-positive Macrococcus caseolyticus (strain KM45013) was isolated from the nares of a dog with rhinitis. It contained a novel 39-kb transposon-defective complete mecB-carrying staphylococcal cassette chromosome mec element (SCCmecKM45013). SCCmecKM45013 contained 49 coding sequences (CDSs), was integrated at the 3' end of the chromosomal orfX gene, and was delimited a...

BACKGROUND Methicillin-resistant coagulase-negative staphylococci (MR-CoNS) are opportunistic pathogens and serve as a large reservoir of staphylococcal cassette chromosome mec (SCCmec). Characterization of SCCmec in MR-CoNS can generate useful information on the mobilization and evolution of this element. METHODOLOGY/PRINCIPAL FINDINGS Non-repetitive MR-CoNS clinical isolates (n = 84; 39 S. ...

OBJECTIVES Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was first reported in remote regions of Western Australia (WA) in 1992 and is now the predominant MRSA isolated in the State. To gain insights into the emergence of CA-MRSA, 2146 people living in 11 remote WA communities were screened for colonization with S. aureus. METHODS Antibiogram analysis, contour-cla...

Seventy-one percent of 76 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from two medical centers in El Paso, Texas, represent three similar pulsed-field gel electrophoresis types. Overall, six pulsed-field types were identified represented by multilocus sequence/staphylococcal chromosomal cassette DNA mec (SCCmec) types: ST5-MRSA-II; ST36-MRSA-II; ST8 (untypeable SCCmec); ...

Staphylococcus aureus and Coagulase-Negative Staphylococci (CoNS) represent harmful pathogenic agents responsible for human and animal infections. The Community-Acquired Methicillin Resistant S. aureus (CA-MRSA) is now considered a worldwide health issue. Methicillin resistance is attributed to the acquisition of the Staphylococcal Cassette Chromosome mec (SCCmec), a resistance island that cont...

BACKGROUND There is increasing frequency of vancomycin-intermediate and -resistant Staphylococcus aureus (VISA and VRSA) isolates identified in clinical practice. There are limited reports evaluating susceptibility patterns and molecular characteristics of these strains. METHODS Laboratory analysis was performed on 13 VRSA and 33 VISA isolates, including susceptibility testing by broth microd...

Staphylococcal cassette chromosome mec (SCCmec) elements confer methicillin resistance to the human pathogen Staphylococcus aureus (methicillin-resistant S. aureus [MRSA]). Recently, the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC) has published new guidelines for classifying different SCCmec elements (3). The new classification of S...

conclusions the study revealed a high prevalence of multi-drug resistance (mdr), class 1 integron, sccmec type iii, and spa type t030 amongst mrsa associated with burn wounds in an iranian hospital. the existence of sccmec type iii in burn patients emphasizes the nosocomial origin of these strains. objectives the aim of this study was to determine the distribution and molecular types of mrsa in...