نتایج جستجو برای: stem cell transplant
تعداد نتایج: 1850382 فیلتر نتایج به سال:
BACKGROUND Minimal criteria for the diagnosis of multiple myeloma are provided. Monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, primary systemic amyloidosis and metastatic carcinoma must be included in the differential diagnosis. Patients with multiple myeloma should not be treated unless they have an increasing M-protein in the serum or urine, development of an...
Glanzmann thrombasthenia is an inherited auto-somal recessive disorder characterized by normal platelet count but lack of platelet aggregation due to absence of platelet glycoprotein IIb/IIIa. The disease usually is associated with mild bleeding, but severe fatal hemorrhage may occur. Allogeneic stem cell transplant is the only curative method of treatment. A literature search showed 18 previou...
Hematopoietic stem cell transplantation has been used for many years to treat various malignant and nonmalignant hematologic conditions. However, the high-dose conditioning regimen can lead to major organ dysfunction, life-threatening infection and bleeding. In the allogeneic setting, graft-versus-host disease may also develop, making post-transplant management complex. Once a transplant recipi...
Allogeneic stem cell transplantation has become a curative treatment option for many patients with haematological malignancies, bone marrow failure syndromes, thalassaemia, sickle-cell disease and some rare disorders of the blood and bone marrow. Ideally, stem cells from the peripheral blood or bone marrow are sourced from sibling donors or from a matched unrelated donor if a sibling donor is n...
In allogeneic stem cell mobilization, peripheral blood stem cell mobilization with filgrastim can be considered standard of care. Poor mobilizers may be at risk for inadequate stem cell collection during apheresis. He we present a successful case of salvage plerixafor use with filgrastim in a haploidentical identical transplant patient.
Polyomavirus type BK-associated nephropathy (BKVAN) develops from reactivation of latent infection in urothelium and kidney tubular epithelium. While BK viremia may occur a variety immunosuppressed states, BKVAN exclusively allografts. We report case middle-aged man with remote history allogeneic hematopoietic stem cell transplant (HSCT) who had chronic disease (CKD) secondary to BKVAN.
In particular, reviewer #2 feels that the study would be strengthened by the separation of CD4+ and CD8+ T cells in the analysis. Importantly, reviewer #1 feels that the potentially valuable software should be publicly available. Of note, both reviewers #1 and #2 feel that specific statements regarding the long-term reconstitution of the T cell repertoire or the treatment regimen, respectively,...
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