Background: This study aimed to evaluate the prescription patterns and safety profiles of oral non-steroidal anti-inflammatory drugs (NSAIDs) in three Chinese hospitals.

BACKGROUND Dregea sinensis Hemsl. plant of the genus Dregea volubilis (Asclepiadaceae), plays a vital role in anticancer, antidepression, and immunoregulation. Steroidal glycosides are the main constituents of this herb, which were significant biological active ingredients. OBJECTIVE The objective of this study is to recognize the mechanism of anticancer, antidepression, and immunoregulation ...

..........................................................................................1 CHAPTER I: INTRODUCTION....................................................................3 CHAPTER II: Steroidal Regulation of synaptic density in the magnocellular division of the medial preoptic nucleus (MPN mag) of the Syrian Hamster..............................19 Introduction.........................

The importance of possible adverse effects on renal function of non-steroidal anti-inflammatory drugs has been widely discussed. Elderly people have been thought to be particularly at risk. We therefore studied simple indices of renal function and plasma potassium in 54 patients with a mean age of 85 years, 27 taking these drugs and 27 controls. Twenty five of our 54 patients were also taking d...

Two new cevanine steroidal alkaloids, impericine (1) and forticine (2) along with known bases delavine (3), persicanidine A (4), and imperialine (5) were isolated from the bulbs of Fritillaria imperialis. The structures of impericine (1) [(20R,22S,25S)-5alpha-cevanin-23-ene-3beta,6beta,16beta-triol] and forticine (2) [(20S,22S,25S)-5alpha-cevanine-3beta,6beta-diol] were determined with the help...

The primary objective of this thesis was to investigate the sterol metabolism of two pathogenic oomycetes, specifically the processes of sterol synthesis and sterol acquisition in the fish pathogen Saprolegnia parasitica (Saprolegniales) and the plant pathogen Phytophthora infestans (Peronosporales). Furthermore, the effects of steroidal glycoalkaloids from Solanaceous plants, on P. infestans, ...

Cytotoxic fractions obtained by purification of the ethanolic extract of Anasterias minuta contain sulfated hexasaccharide glycosides. These compounds show antifungal activity against Cladosporium cucumerinum. Introduction Extracts and saponins isolated from starfish show a broad spectrum of biological effects: cytotoxic, hemolytic, antifungal and antiviral activities [1]. Although a high numbe...

Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Only one of 82 patients who were treated with etoricoxib reported reactions. We can conclude that et...