Adsorption of Streptococcus mutans on hydroxyapatite and chemically treated hydroxyapatite was studied. Zeta potentials of the surfaces were measured. Chemically treated hydroxyapatite gave higher zeta potentials and lower S mutans adsorption.

We report the draft genome sequences of PKUSS-HG01 and PKUSS-LG01, two clinical isolates of Streptococcus mutans from human dental plaque. The genomics information will facilitate the study of the mechanisms of pathogenicity and evolution of S. mutans.

Streptococcus mutans is normally alpha- or gamma-hemolytic on blood agar plates. However, three recently isolated S. mutans strains were observed to elicit beta-hemolysis. The production and nature of a hemolytic substance were studied.

Dental caries is the most common infectious disease affecting humans. The principal causative agents are a group of streptococcal species collectively referred to as the mutans streptococci of which Streptococcus mutans and Streptococcus sobrinus are the most important agents of human caries. This review outlines what is currently known about these ubiquitous pathogens and discusses novel metho...

Streptococcus mutans strains were isolated from cohorts of Brazilian nursery school children and genotyped by arbitrarily primed PCR and restriction fragment length polymorphism analysis. Of 24 children with two to five S. mutans isolates, 29% carried two or more genotypes. The presence of matching genotypes of S. mutans among children attending one nursery suggests horizontal transmission.

Correction After publication of the original article [1] it came to the publishers attention that one name had been inadvertently misspelt. The correct authors' list should read as indicated above. We apologize for any inconvenience this has caused. and verification of the transcriptional regulatory response network of Streptococcus mutans upon treatment with the biofilm inhibitor carolacton. v...

Streptococcus mutans is the major pathogen of dental caries and occasionally causes infective endocarditis. Here we report the complete genome sequence of serotype k S. mutans strain LJ23, which was recently isolated from the oral cavity of a Japanese patient.

Streptococcus mutans and Streptococcus sobrinus are known to be associated with the development of dental caries. In this study these bacteria were detected in pre-school children (each with primary dentition, age range 3-5 years, n = 60) using a PCR method, and then their presence was compared with the incidence of dental caries over a 1-year period. Plaque samples were collected from all erup...

Many studies have revealed correlation between serum or salivary immunoglobulin concentration and the progress of caries. Pathogens residing in the oral cavity can stimulate immune cells to produce cytokines. Antibacterial cellular reaction of T-cells in course of caries is related to the expression of superficial antigens of Streptococcus mutans. Interleukin-1β (IL-1β) – one of the most import...

The frequency of nitrosoguanidine-induced mutation for streptomycin-, bacitracin- and rifampicin-resistance was measured in Streptococcus mutans during synchronous replication after release from chloramphenicol inhibition. A clear peak of mutagenesis for each marker was observed at certain times during synchronous replication. These times were different for individual markers; the times of peak...