BACKGROUND We aimed to compare the incremental value of contrast myocardial perfusion imaging (MPI) for the detection of intermediate versus severe coronary artery stenosis during dipyridamole-atropine echocardiography (DASE).Wall motion (WM) assessment during stress-echocardiography demonstrates suboptimal sensitivity to detect coronary artery disease (CAD), particularly in patients with isola...

BACKGROUND Acute rest single-photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI) has high predictive value for acute coronary syndrome (ACS) in emergency department patients. Prior studies have shown excellent agreement between rest/stress computed tomography perfusion (CTP) and SPECT-MPI, but the value of resting CTP (rCTP) in acute chest pain triage remains unclear. W...

BACKGROUND Fractional flow reserve (FFR) measured on catheterization is now widely used for the diagnosis of functional myocardial ischemia in patients with coronary artery disease (CAD). FFR, however, is invasive and carries potential procedural complications. Therefore, the aim of this study was to compare the diagnostic capability in functionally significant stenosis identified on FFR, betwe...

MPI implementations that support the highest level of thread safety for user programs, MPI THREAD MULTIPLE, are becoming widely available. Users often expect that different threads can execute independently and that the MPI implementation can provide the necessary level of thread safety with only a small overhead. The MPI Standard, however, requires only that no MPI call in one thread block MPI...

This study sought to establish worldwide and regional diagnostic reference levels (DRLs) achievable administered activities (AAAs) for single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Reference serve as radiation dose benchmarks compare individual laboratories against aggregated data, helping identify sites in greatest need of reduction interventions. DRLs ...

OBJECTIVE Anatomic coronary artery disease (CAD) can be determined by coronary angiography (CAG) in patients with normal stress single photon emission tomography (SPET) myocardial perfusion imaging (MPI). Coronary angiography results of patients with negative exercise MPI and the prognosis of these patients (CAG-diagnosed CAD vs. non-CAD) were investigated in the current study. SUBJECTS AND M...

Nuclear imaging has an established clinical role in the non-invasive diagnosis of coronary artery disease (CAD), allowing accurate patient stratification and allocation to the best form of treatment. Semi-quantitative assessment of regional myocardial perfusion with single-photon emission computed tomography (SPECT) is a noninvasive, robust, and widely available method of assessing myocardial i...

BACKGROUND Correction of motion has become feasible on cadmium-zinc-telluride (CZT)-based SPECT cameras during myocardial perfusion imaging (MPI). Our aim was to quantify the motion and to determine the value of automatic correction using commercially available software. METHODS AND RESULTS We retrospectively included 83 consecutive patients who underwent stress-rest MPI CZT-SPECT and invasiv...

OBJECTIVES The aim of the present study was to determine the long-term prognostic value provided by the exercise electrocardiographic (ECG) response to nuclear myocardial perfusion imaging (MPI) in the evaluation of patients with chest pain, focusing on patients with a discrepancy between the two tests. METHODS A total of 1460 consecutive patients (777 female; 62.6 ± 11.4 years) undergoing ex...