Background: The cultivation of saffron is expanding through the southeast of Iran, and allergy to saffron pollen occurs in workers involved in processing this plant. We aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. Methods: The N-terminal amino acid sequence of Cro s 1, an allergen from saff...

Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison was developed. Novelty of the model is threefold. First, a sample of random structure comparisons is restricted to molecules of the same size and shape as the superposition of interest. Second, careful selection of the ...

This paper establishes a new technique that enables us to access some fundamental structural properties of instanton Floer homology. As an application, we establish, for the first time, relation between homology $3$-manifold or null-homologous knot inside and Heegaard diagram knot. We further use this compute families $(1,1)$-knots, including all torus knots in $S^3$, which were mostly unknown ...

We propose a notion of minimal free resolutions for differential modules, and we prove existence uniqueness results such resolutions. also take the first steps toward studying structure modules. Our main result in this direction explains sense which resolution module is deformation its homology; leads to structural that mirror classical theorems about

Sana Khalid1, Sobia Idrees1, Hina Khalid1, Bilal Hussain1, Sandeep Tiwari2, Syed Shah Hassan2, Artur Silva3, Vasco Azevedo2 and Syed Babar Jamal2* 1Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Pakistan 2Departamento de Biologia Geral, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais, Brazil 3Instituto de Ciências Biológica...

Knowing the tertiary structure of proteins is important to predict protein function and to achieve rational drug design. However, huge amounts of money and time are needed to determine tertiary structures by experimental method. Only a small number of protein structures have been experimentally determined; therefore, prediction of the tertiary structure of proteins by computer should be of grea...

Although protein structure prediction has made great progress in recent years, a protein model derived from automated prediction methods is subject to various errors. As methods for structure prediction develop, a continuing problem is how to evaluate the quality of a protein model, especially to identify some well-predicted regions of the model, so that the structural biology community can ben...

There is a large class of applications in computational structural biology for which atomic-level representation is crucial for understanding the underlying biological phenomena, yet explicit atomic-level modeling is computationally prohibitive. Computational protein design, homology modeling, protein interaction prediction, docking and structure recognition are among these applications. Models...

We investigate the relative cohomology and relative homology theories of $F$-Gorenstein modules, consider the relations between classical and $F$-Gorenstein (co)homology theories.