INTRODUCTION Measurement errors and questionnaire effects in survey data can have substantial impact on estimates of statistical relationships. Although the customer satisfaction literature contains some discussion of scaling issues (Westbrook and Oliver 1981), statistical models of customer satisfaction have not explicitly recognized measurement issues. This paper enhances the traditional mode...

Structural economic models allow one to analyze counter-factuals when economic system change and to evaluate the well being of economic agents. A key element in such analysis is the ability to identify the primitive functions and distributions of the economic models that are employed to describe the economic phenomena under study. Recent developments in nonparametric identification of structura...

The first proton transfer in the bacteriorhodopsin photocycle takes place during the L → M transition. Structural details of the pre proton transfer L intermediate have been investigated using experiments and computations. Here, we assess L-state structural models by performing hybrid quantum mechanical/molecular mechanical molecular dynamics and excitation energy calculations. The computations...

Stable isotope-labeling methods, coupled with novel techniques for detecting fast-relaxing NMR signals, now permit detailed investigations of paramagnetic centers of metalloproteins. We have utilized these advances to carry out comprehensive assignments of the hyperfine-shifted (13)C and (15)N signals of the rubredoxin from Clostridium pasteurianum (CpRd) in both its oxidized and reduced states...

Recent technological improvements in crystallographic data collection have led to a surge in the number of protein structures being determined at atomic or near-atomic resolution. At this resolution, structural models can be expanded to include anisotropic displacement parameters (ADPs) for individual atoms. New protocols and new tools are needed to refine, analyze and validate such models opti...

RNAs fold into distinct molecular conformations that are often essential for their functions. Accurate structure modeling of complex RNA motifs, including ubiquitous non-canonical base pairs and pseudoknots, remains a challenge. Here, we present an NMR-guided all-atom discrete molecular dynamics (DMD) platform, iFoldNMR, for rapid and accurate structure modeling of complex RNAs. We show that sp...

In this paper, we study several structural models of amorphous silicon, and discuss structural and electronic features common to all. We note spatial correlations between short bonds, and similar correlations between long bonds. Such effects persist under a first principles relaxation of the system and at finite temperature. Next we explore the nature of the band tail states and find the states...

Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we use chromosome-chromosome contact data as knowledge-based constraints for large-scale three-dimensional models of the human diploid genome. The resulting models remain minimally entangled and acquire several functiona...

This thesis uses a literature review to describe the latest progress in the models used to describe interest rate term structure (TS). The thesis emphasises macroeconomic variables and models, as these elements have become an essential part of TS modelling in the 21 st century. Although this type of literature review has not been conducted before, the rapid development of numerous kinds of mode...

We derive displacement equations for Rayleigh and Love waves in simple structural models for point sources in order to better understand source effects on their wavefields and radiation patterns. In doing so, we analytically demonstrate the existence of surface waves in these Earth models. Rayleigh and Love wave radiation patterns are found to mimic the P and SH radiation patterns, respectively...