نتایج جستجو برای: structurally mediated model

تعداد نتایج: 2480648  

2004
Ilan Samish Eran Goldberg Oksana Kerner Avigdor Scherz

Our analysis demonstrates that backbone-mediated interhelical hydrogen-bonds cluster laterally in the conserved core of transmembrane helical proteins. Each residue's propensity to bear these interactions is in correlation with the residue's packing-value scale; giving biophysical meaning to this phenomenological scale. Residues participating in such an intersubunit, structurally conserved H-bo...

Journal: :Proceedings of the American Mathematical Society 1973

Journal: :Rocky Mountain Journal of Mathematics 2008

Journal: :Logical Methods in Computer Science 2015

Christian Thomas, Ole Simon, Oliver Grauer, Petra Hundehege, Sven Meuth, Thomas Müntefering, Tobias Ruck,

TASK-3, a two-pore-domain (K2P) potassium channel, has been implicated as important regulator for the effector function and proliferation of T-cells. Interestingly, TASK-3 has also a functional impact on tumor cells. Therefore, we sought to investigate whether TASK3 modulation might have a therapeutic potential for malignant gliomas by a variety of phenotypical and functional in vitro assays mi...

Journal: :Environmental Health Perspectives 1984
R Loch-Caruso J E Trosko I A Corcos

Intercellular communication most likely plays a significant coordinating role in morphogenesis. Blockage of a specific type of intercellular communication, that mediated by gap junctions, has been proposed as a mechanism of action of some teratogens. Several glycol ethers have recently been shown to be teratogenic in laboratory animals. Because these compounds are negative in genotoxic assays, ...

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