نتایج جستجو برای: subacute combined degeneration

تعداد نتایج: 446376  

2013
Ji Won Yang Ji-Young Han Moon-Woo Seong Jung-Joon Sung Sung Sup Park Kwang-Woo Lee

Autosomal dominant hereditary spastic paraplegia (AD-HSP) is due to mutations in the "spastin" gene (SPAST gene) encoding the AAA protein. The main clinical features of "pure" HSP are progressive lower-limb spasticity with corticospinal tracts and dorsal column degeneration without peripheral neuropathy. Here we report the case of HSP with novel SPAST gene mutation that misdiagnosed with subacu...

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2018

Journal: :Brain : a journal of neurology 1988
J D England A K Asbury E K Rhee A J Sumner

Doxorubicin (Adriamycin) is an autofluorescent anthracycline antibiotic that acts as a DNA intercalator. Following intraneural microinjection of 3 micrograms of doxorubicin into rat tibial nerve, fluorescence microscopy indicated that it is transported retrogradely to anterior horn cell bodies. Subsequently, these motor neurons underwent a progressive subacute degeneration that occurred over a ...

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