BACKGROUND Primary care clinicians' attitudes may differ based on patients' substance dependence type (alcohol, other drugs or both). AIM The aim of this study was to evaluate whether substance dependence type is associated with primary care quality (PCQ). METHODS We tested the association between substance dependence type and six PCQ scales of the Primary Care Assessment Survey (PCAS) in m...

The development of substance dependence requires the initiation of substance use and the conversion from experimental use to established use before development of dependence. Numerous large twin studies have indicated a significant genetic contribution to this process. Genetic studies to date have been most successful at identifying genetic factors that influence the transition from regular use...

IMPORTANCE Transgender youth, including adolescent and young adult transgender women assigned a male sex at birth who identify as girls, women, transgender women, transfemale, male-to-female, or another diverse transfeminine gender identity, represent a vulnerable population at risk for negative mental health and substance use outcomes. Diagnostic clinical interviews to assess prevalence of men...

264 The fact that alcohol is an addictive drug has been known to man for millennia. Alcohol abuse/dependence is the most common substance-related disorder. A drug can be defined as a substance that produces tolerance (increasingly large amounts are needed to produce the same effect) and withdrawal (psychological and physical distress develop after substance use ceases). The addicted person suff...

OBJECTIVES We investigated whether there were gender differences in chronic medical, psychiatric, and substance-dependence disorders among jail inmates and whether substance dependence mediated any gender differences found. METHODS We analyzed data from a nationally representative survey of 6982 US jail inmates. Weighted estimates of disease prevalence were calculated by gender for chronic me...