Distribution profiles of superoxide dismutase isoenzymes in various tissues of rabbits with the Vx-2 carcinoma in the maxillary sinus were compared with those of control rabbits. Copper- and zinc-containing superoxide dismutase (Cu,Zn-SOD) activity in the liver of rabbits decreased significantly 3 weeks after transplantation. Manganese-containing superoxide dismutase (Mn-SOD) activity did not d...

BACKGROUND AND PURPOSE The purpose of this study was to determine the distribution of polyethylene glycol-conjugated superoxide dismutase in the brain, cerebrospinal fluid, and various organs. METHODS Distribution of iodine-125-labeled polyethylene glycol-conjugated superoxide dismutase was determined in three groups of male Sprague-Dawley rats: a normotensive sham control group (n = 9) and g...

Amyotrophic lateral sclerosis is a rapidly progressing fatal neurodegenerative disease characterized by the presence of protein inclusions within affected motor neurons. Endoplasmic reticulum stress leading to apoptosis was recently recognized to be an important process in the pathogenesis of sporadic human amyotrophic lateral sclerosis as well as in transgenic models of mutant superoxide dismu...

trichosanthes kirilowii, an important economic plant in china, is sensitive to chilling. to investigate the effect of abscisic acid (aba) treatment on the chilling tolerance of trichosanthes kirilowii maxim, different concentrations of aba were sprayed on trichosanthes kirilowii leaves and the resulting catalase (cat) and superoxide dismutase (sod) activities and the malondialdehyde (mda) conte...

selenium is an essential element for humans, therefore, adding it to plants is convenient for biofortification. thus, the aim of this work was to analyze experimentally the ability of sodium selenite to increase the concentration of se and modify the antioxidant activity in tomato plants. we used plants of the toro hybrid variety and applied three treatments: 0, 2 and 5 mg l-1 of selenium as so...

subclinical mastitis is considered as one of the most prevalent diseases in dairy cows, causing drasticloss in the dairy industry. oxidative stress, induced by reactive oxygen species (ros), is believed to be aprimary factor in various cattle diseases including mastitis, but there are few studies regarding the role ofros in subclinical mastitis. this study was undertaken to i) study the changes...

objective: electro-magnetic radiation (emr) is emitted from mobile phones. various researches have shown relationships between mobile phone emr exposure to cancer and neurologic damages. this study aims to investigate the effects of mobile phone emr on brain antioxidant enzyme activity and the learning process. methods: rat pups and their dames were exposed to emr for 3 h per day from p2 to p1...

objective(s): amyotrophic lateral sclerosis (als), a fatal progressive neurodegenerative disorder, is the most common motor neuron disease in european populations. approximately 10% of als cases are familial (fals) and the other patients are considered as sporadic als (sals). among many als causing genes that have been identified, mutations in sod1 and c9orf72 are the most common genetic causes...

background: atopic dermatitis is a public health problem worldwide. increment of reactive oxygen species (ros) produc­tion may be one of the contributing factors of tissue damage in atopic dermatitis. the present study was designed to deter­mine the effect of vitamins e and/or d on erythrocyte superoxide dismutase and catalase activities in patients with atopic dermati­tis. methods: in a random...

superoxide dismutase (sod) is an important antioxidant that protects many types of cells from the free radical damage. one of the possible ways for the use of sod is its incorporation in liposomes. the aim of this study was to investigate the effect of cationic phospholipids on the entrapment of human erythrocyte superoxide dismutase (cu/zn sod) in liposomes. also, in the present study, we exam...