How nerves transmit their signals to regulate activity of smooth muscle is of fundamental importance to autonomic and enteric physiology, clinical medicine, and therapeutics. A traditional view of neurotransmission to smooth muscles has been that motor nerve varicosities release neurotransmitters that act on receptors on smooth muscles to cause their contraction or relaxation via electromechani...

We analyze alternating descent algorithms for minimizing the sum of a quadratic function and block separable non-smooth functions. In case the quadratic interactions between the blocks are pairwise, we show that the schemes can be accelerated, leading to improved convergence rates with respect to related accelerated parallel proximal descent. As an application we obtain very fast algorithms for...

Exaggerated contraction of airway smooth muscle is the major cause of symptoms in asthma, but the mechanisms that prevent exaggerated contraction are incompletely understood. Here, we showed that integrin α9β1 on airway smooth muscle localizes the polyamine catabolizing enzyme spermidine/spermine N1-acetyltransferase (SSAT) in close proximity to the lipid kinase PIP5K1γ. As PIP5K1γ is the major...

Definition of bi-supra topological space via graph theory was introduced in this study. We also studied some concepts related bi supra-topological theory. "At least many theorems were proofed as a characterization and examples to explain the subject".

Supra-glacial lakes (i.e., ponds of melting water on ice sheet) in Greenland have attracted extensive global attention during the recent years. To understand the important role they play in glacier movement, sea level rise, and climate change, scientists need to learn where these lakes are, when they form, and how they change in each melting season and across multiple years. This requires detec...

Supra-glacial lakes (i.e., ponds of melting water on ice sheet) in Greenland have attracted extensive global attention during the recent years. To understand the important role they play in glacier movement, sea level rise, and climate change, scientists need to learn where these lakes are, when they form, and how they change in each melting season and across multiple years. This requires detec...

BACKGROUND Supra-pancreatic lymph node dissection is important in patients undergoing laparoscopic gastrectomy (LG) for gastric cancer. A clear view of the supra-pancreatic area is necessary for precise dissection of supra-pancreatic lymph nodes without injury to the pancreas. This retrospective study assessed the efficacy of T-shaped gauze (TSG) in retracting the pancreas during supra-pancreat...