Aim and objective: The purpose of this study was to develop microemulsion formulations for topical delivery bifonazole with an objective increase the solubility drug. Methods: Total 5 were developed using water titration method. Capmul Pg-12 (oil), Tween-80: (surfactant) Propylene glycol (co-surfactant) used in different ratio based on emulsification efficiency. Prepared evaluated parameters li...

in this study formation and properties of o/w emulsion stabilized by a mixture of sodium caseinate (2, 5 and 10 wt %) and non-ionic emulsifier tween 80, sorbitan mono-9-octadecenoate, (0, 0.5, 1 and 1.5 wt %) were investigated at various ph values(3, 5 and 7) and calcium ion concentrations (0, 0.2, 0.4 and 0.6 wt%). emulsion samples were prepared by using a sonicator with a nominal power output...

Firstly,we are study to formulate and test a topical gel containing of Itraconazole micro- emulsion (ITZ). The Formulation micro researchis necessary before its thepreformulation Itraconazole. To estimatethe maximal solubility ITZ in oils, surfactants co- were investigated estimatefilling material potential. In reference the region, with Karanj oil as phase, use surfactant Tween-80 aDiamethyl C...

The addition of Tween 80 and sucrose monopalmitate, nonionic surfactants, to fungal cultures resulted in marked increases in yields of the enzymes cellulase, amylase, sucrase, beta-1 --> 3 glucanase, xylanase, purine nucleosidase, and benzoyl esterase. The action appears to be an effect of the surfactant on cell permeability.

objective(s):  the aim of this study was to prepare a nanosuspension formulation as a new vehicle for the improvement of the ocular delivery of vitamin a.  material and methods:   formulations were designed based on full factorial design. a high pressure homogenization technique was used to produce nanosuspensions. fifteen formulations were prepared by the use of different combinations of surfa...

The structures of micelles of the surfactant polysorbate 80 (Tween 80) in 0-50% aqueous dimethyl sulfoxide (DMSO) solutions (pH 7.2, ionic strength 2.44 mM) were investigated by means of small-angle X-ray scattering. At DMSO concentrations of 0-20%, core-shell cylinder micelles formed, and at 30-50% DMSO, core-shell discus micelles formed, that is, changing the hydrophobicity of the DMSO solven...

Introduction of fuel hydrocarbons and inorganic compounds (heavy metals) into the soil, resulting in a change of the soil quality, which is likely to affect use of the soil or endangering public health and ground water. This study aimed to determine a series of parameters to remediation of TPH and heavy metals contaminated soil by non-ionic surfactants- chelating agents washing process. In this...

The aim of this investigation was to design and develop nanoemulsions as novel delivery systems for rapamycin. Phase behavior of quaternary systems composed of Traicetin (as oil), various surfactants and co-surfactants and water at different surfactant/co-surfactant weight ratios were investigated by the construction of phase diagrams. Formulations were taken from the o/w NE region of the phase...