Swallowing is an important function to separate the airway and the oesophagus. Dysfunction of this mechanism may lead to aspiration of pathogenic oropharyngeal contents. The disorder of swallowing function can be evaluated by the simple two-step swallowing provocation test (STS-SPT) and repetitive saliva swallowing test (RSST) [1, 2]. Both screening tests are safe, rapid and of low cost. Recent...

Surface electrical stimulation is currently used in therapy for swallowing problems, although little is known about its physiological effects on neck muscles or swallowing. Previously, when one surface electrode placement was used in dysphagic patients at rest, it lowered the hyolaryngeal complex. Here we examined the effects of nine other placements in normal volunteers to determine 1) whether...

The recent application of neurostimulation techniques to enhance the understanding of swallowing neural plasticity has expanded the focus of rehabilitation research from manipulation of swallowing biomechanics to manipulation of underlying neural systems. Neuromodulatory strategies that promote the brain's ability to reorganize its neural connections have been shown to hold promising potential ...

We previously prepared and pharmaceutically evaluated ginger orally disintegrating (OD) tablets, optimized the base formulation, and carried out a clinical trial in healthy adults in their 20 s and 50s to measure their effect on salivary substance P (SP) level and improved swallowing function. In this study, we conducted clinical trials using the ginger OD tablets in older people to clinically ...

BACKGROUND Hyperbilirubinemia (HB) occurs in 90% of preterm newborns. HB induces acute neurological disorders (somnolence, abnormal tone, feeding difficulties, auditory dysfunction) and alterations in respiratory control. These findings suggest brainstem neurotoxicity that could also affect swallowing centers. OBJECTIVE To test the hypothesis that HB impairs nutritive swallowing (NS) and swal...

Human swallowing represents a complex highly coordinated sensorimotor function whose functional neuroanatomy remains incompletely understood. Specifically, previous studies have failed to delineate the temporo-spatial sequence of those cerebral loci active during the differing phases of swallowing. We therefore sought to define the temporal characteristics of cortical activity associated with h...

UNLABELLED Neuroleptic drugs are used in several mental disorders, but are suspected of causing oropharyngeal dysphagia, mainly in the elderly. AIM To study the effect of neuroleptic agents on swallowing of institutionalized older people. MATERIAL AND METHOD A cross sectional study of swallowing in 47 subjects that either used or did not use neuroleptic drugs. Bedside swallowing tests with ...

Swallowing problems can affect as many as one in three patients in the period immediately after stroke. Despite this, in the majority of cases, recovery usually occurs to a safe level after a month or two. In this review, we show how the organization of the cortical projections to swallowing muscles can account for many of the clinical observations on swallowing after stroke and explain why rec...

ABSTRACT Purpose: to verify the correlation between oropharyngeal dysphagia and quality of life in elderly people late phase after stroke. Methods: a retrospective cross-sectional study, whose data were obtained by analyzing database composed 30 All participants underwent clinical instrumental evaluation swallowing through fiberoptic endoscopic swallowing. The related was analyzed using Quality...

HYPOTHESIS Fiberoptic endoscopic evaluation of swallowing (FEES) will identify patients who are at high risk for pulmonary aspiration due to swallowing dysfunction after prolonged intubation. Based on the results of FEES, dietary recommendations can be made to decrease the incidence of aspiration after prolonged intubation. DESIGN Patients who were intubated for at least 48 hours were evaluat...