Because the aberrantly activated phosphoinositide 3-kinase (PI3K)/Akt pathway renders tumor cells resistant to cytotoxic insults, including those related to anticancer drugs, inhibition of the pathway may possibly restore or augment the effectiveness of chemotherapy. Using the human malignant glioma cell lines U87, A172, LN18, and LN229, we examined effects of the PI3K inhibitor LY294002 on bot...

phenolic and flavonoid compounds are secondary metabolites of plants which possess various activities such as anti-inflammatory, analgesic, anti-diabetes and anticancer effects. it has been established that these compounds can scavenge free radicals produced in the body. because of this ability, not only the plants containing phenolic and flavonoid compounds but also, the pure compounds are use...

uv/tio2 photocatalysis of chelated copper in aqueous solutions has been performed starting from cu(ii)-tartaric acid, cu(ii)-citric acid, cu(ii)-edta and cu(ii)-dtpa,in the presence of oxygen and at acidic ph. the photocatalytic reaction obeys first-order kinetic equation. the influence of cu(ii) on photocatalytic oxidation of organic ligands and how the various organics will affect the treatmen...

BACKGROUND Breathing the inert gas Xenon (Xe) enhances hypothermic (HT) neuroprotection after hypoxia-ischemia (HI) in small and large newborn animal models. The underlying mechanism of the enhancement is not yet fully understood, but the combined effect of Xe and HT could either be synergistic (larger than the two effects added) or simply additive. A previously published study, using unilatera...

We demonstrate the surface-plasmon-induced enhancement of Förster resonance energy transfer (FRET)using a model multilayer core-shell nanostructure consisting of an Au core and surrounding FRET pairs, i.e., CdSe quantum dot donors and S101 dye acceptors. The multilayer configuration was demonstrated to exhibit synergistic effects of surface plasmon energy transfer from the metal to the CdSe and...

In the present work, novel nanotool called 'nano-embedded fungus' formed by impact of synergistic association of ZnO-nanorods and fungus Piriformospora indica DSM 11827, for growth of Brassica oleracea var. botrytis (Broccoli) is reported. ZnO-nanorods were synthesized by mechanical assisted thermal decomposition process and characterized by scanning electron microscopy (SEM) for morphology, X-...

a series of copper and cobalt substituted nanospinel ferrites have been synthesized by the hydrothermal method. these compounds were characterized by ft-ir, xrd, edx, sem and vsm techniques. all of the synthesized nanospinel ferrites were found to be highly efficient and magnetically recoverable in the solvent-free synthesis of substituted 2,6-(2-hydroxybenzyl)-phenols (trisphenols). a wide ran...

Understanding the mechanism of surface-enhanced Raman scattering (SERS) of molecules on semiconductor nanostructures is directly related to our capabilities of designing and optimizing new SERS-active substrates for broad applications in the field of molecular detection and characterization. Here, we present an exploration of using cuprous oxide nanostructures with hierarchical porosity for enh...

The nanocaps array of TiO₂/Ag bilayer with different Ag thicknesses and co-sputtering TiO₂-Ag monolayer with different TiO₂ contents were fabricated on a two-dimensional colloidal array substrate for the investigation of Surface enhanced Raman scattering (SERS) properties. For the TiO₂/Ag bilayer, when the Ag thickness increased, SERS intensity decreased. Meanwhile, a significant enhancement wa...

Prostate cancer (PC) and benign prostatic hyperplasia (BPH) are the most common diseases diagnosed in men, early and accurate differential diagnosis of which is an important task. DCE-MRI plays an essential role for cancer detection and characterization. Previous studies have tried to characterize time-enhancement curves of malignant and benign prostate tissues, and thereby to deduce the best d...